Identification of a novel base J binding protein complex involved in RNA polymerase II transcription termination in trypanosomes트리파노솜에서 RNA 중합효소 II 전사 종결에 관여하는 새로운 염기 J 결합 단백질 복합체의 확인Research Article Published on 2020-02-212022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Ablation addition African sleeping sickness analysis Analysis base binding binding domain cause co-IP complex dephosphorylation derepression described DNA downstream genes Epigenetic eukaryotes expand expressed expression Factors gene cluster gene clusters Gene Expression Genome homolog Host Human humans identification identify immune evasion Interaction involved lead leads Leishmania mammalian mass spectrometry mechanism Modification mutant mutants organism Organisms organized phosphatase promoter Protein protein complex Protozoa Reciprocal recruitment regulate regulated Regulatory residue RNA RNA Polymerase II RNA-Seq RNAi RT-PCR shown significantly silent sleeping sickness specific proteins sucrose surface Surface glycoprotein termination thymine Transcription transcription start sites Trypanosoma Trypanosoma brucei Trypanosome upstream variant Variant Surface Glycoprotein Wdr82 yeast [DOI] 10.1371/journal.pgen.1008390 PMC 바로가기 [Article Type] Research Article
Transcriptional and genomic parallels between the monoxenous parasite Herpetomonas muscarum and Leishmania일산화 기생충 Herpetomonas muscarum과 Leishmania 사이의 전사 및 게놈 유사점Research Article Published on 2019-11-112022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] biting flies causative agents conserved Culture Diptera disease Drosophila melanogaster early stage early stages event Gene regulation Genome genomic highlighting Host hosts Human identify in vitro infect Infection infections insect Insects Interaction Leishmania Leishmania major Leishmaniasis less mammal mammalian mammals monoxenous parasites MOST Neglected NTDs parasite parasites Regulation reported Sand similarity sleeping sickness Transcriptome Transmission transmitted Tropical Diseases Trypanosome turn vector [DOI] 10.1371/journal.pgen.1008452 PMC 바로가기 [Article Type] Research Article
A Conserved DNA Repeat Promotes Selection of a Diverse Repertoire of Trypanosoma brucei Surface Antigens from the Genomic Archive보존된 DNA 반복은 게놈 아카이브에서 트리파노소마 브루세이 표면 항원의 다양한 레퍼토리 선택을 촉진합니다Research Article Published on 2016-05-052022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] activated addition African African trypanosomiasis antigenic variation archive assumption bloodstream catastrophic Cell cell cycle Chromosomal translocation Chromosomal translocations chromosome chronic condition conserved demonstrated DNA DNA sequence Donor event expression gene conversion genetic change Genome genomic homolog homology Host Hypothesis identify implicated induce infect Infection iteration mammalian manipulation natural infection observation observé outcome parasite pathogen Pathogens promote Protein proximal Recombination recombination event reduction in Region Repeat repertoire required selected Selection sequence silent species Support surface Surface glycoprotein switching synthetic tested the cell These data transcribed translocation Trypanosoma Trypanosoma brucei Trypanosome trypanosomiasis Variant Surface Glycoprotein VSG [DOI] 10.1371/journal.pgen.1005994 PMC 바로가기 [Article Type] Research Article
Investigation of the morphological diversity of the potentially zoonotic Trypanosoma copemani in quokkas and Gilbert’s potoroosArticle Published on 2015-09-012023-06-02 Journal: Parasitology [Category] 조류인플루엔자, [키워드] marsupial novel life-cycle stages pathogenesis. Potorous gilbertii Setonix brachyurus T. copemani Trypanosome [DOI] 10.1017/S0031182015000785 PMC 바로가기
The within-host dynamics of African trypanosome infectionsArticle Published on 2015-08-192023-05-31 Journal: Philosophical Transactions of the Royal Society B: [Category] Fulltext, 조류인플루엔자, [키워드] Trypanosoma antigenic variation quorum sensing Transmission Trypanosome within-host dynamics [DOI] 10.1098/rstb.2014.0288 PMC 바로가기
[Atypical human trypanosomoses]Article Published on 2014-07-012023-06-02 Journal: Med Sante Trop [Category] 조류인플루엔자, [키워드] atypical trypanosomiasis Trypanosoma evansi Trypanosoma lewisi Trypanosome trypanosomiasis. [DOI] 10.1684/mst.2014.0346 PMC 바로가기