Evaluation of indirect sequence-specific magneto-extraction-aided LAMP for fluorescence and electrochemical SARS-CoV-2 nucleic acid detectionArticle Published on 2023-01-152022-11-15 Journal: Talanta [Category] SARS, 변종, 치료기술, 치료제, [키워드] amplification approach circumvent clinically Disadvantages Electrochemical LAMP Host in silico inhibitor investigated isothermal isothermal amplification Magnetic sequence-specific target enrichment molecular NAAT nucleic acid Nucleic acid detection PCR polymerase probe qRT-PCR Quantitative Quantitative real-time LAMP real-time reverse transcriptase restrict SARS-CoV-2 SARS-CoV-2 nucleic acid SARS-CoV-2 variant sensitivity sequence serum turn [DOI] 10.1016/j.talanta.2022.123809 PMC 바로가기
Impact of the COVID-19 pandemic on return and risk transmission between oil and precious metals: Evidence from DCC-GARCH modelResearch article Published on 2022-12-012022-10-05 Journal: Resources Policy [Category] 진단, [키워드] addition changed condition contribute correlation COVID-19 pandemic DCC-GARCH debates empirical finding Evidence Impact Oil pandemic positive Precious metals risk seeking The COVID-19 Transmission turn weakened [DOI] 10.1016/j.resourpol.2022.102939 [Article Type] Research article
Assessing a fossil fuels externality with a new neural networks and image optimisation algorithm: the case of atmospheric pollutants as confounders to COVID-19 lethalityOriginal Paper Published on 2022-11-162022-11-01 Journal: Epidemiology and Infection [Category] COVID-19, MERS, [키워드] adopted Affect Air pollution Algorithm approach Assessing atmospheric causal relationship China collected data confounder coronavirus COVID-19 COVID-19 epidemic deaths economic growth GDP generate Health image learning Implications machine learning network Neural neural networks Spread Transport turn Variation [DOI] 10.1017/S095026882100248X PMC 바로가기 [Article Type] Original Paper
A review on computer-aided chemogenomics and drug repositioning for rational COVID-19 drug discoveryArticle Published on 2022-11-012022-11-15 Journal: Chemical biology & drug design [Category] 변종, 신약개발, 치료기술, 치료제, [키워드] analyzed application assist chemogenomics compounds Computational drug computational drug discovery Computational methods coronavirus coronavirus disease CoV COVID-19 CoVs drug candidate Drug discovery drug repositioning drugs Efficiency epidemic diseases example feasible Host in silico approaches molecular docking other variants outcome Polypharmacology polypharmacology. Protein provide reflected reported Spread therapeutic target time-consuming Toxicity turn unique virus [DOI] 10.1111/cbdd.14136 PMC 바로가기
B-cell repopulation dynamics and drug pharmacokinetics impact SARS-CoV-2 vaccine efficacy in anti-CD20-treated multiple sclerosis patientsArticle Published on 2022-11-012022-11-15 Journal: European journal of neurology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] 95% CI 95% confidence interval Affect anti-CD20 anti-CD20 treatment antibody Antibody Response Antibody titers B cell B cells B-cell B-cell depletion Blood booster cellular response Cohort correlated detectable develop Efficacy Guidance humoral identify IgG^{+} interleukin-13 Logistic regression median memory multiple sclerosis naïve no correlation Odds ratio Patient patients predict predictor Probability recent rituximab S1 domain SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine Seroconversion T-cell Response treated Treatment turn vaccination vaccine responses [DOI] 10.1111/ene.15492 PMC 바로가기
Forty Years of Molecular Diagnostics for Infectious DiseasesArticle Published on 2022-10-192022-11-15 Journal: Journal of Clinical Microbiology [Category] 유전자 메커니즘, 진단, 치료기술, [키워드] amplification assumed Care coronavirus disease COVID-19 detect diagnostic diagnostic molecular microbiology diagnostics DNA DNA sequencing elapsed Factors Health in vitro Infectious disease Intersection knowledge Magnetic beads microbial molecular nucleic acid nucleic acids nucleotide nucleotide array pandemic pathophysiologic PCR Perspective point of care progression quantification Quantitative real-time quantitative PCR Sequencing syndromic panel. turn Year [DOI] 10.1128/jcm.02446-21 PMC 바로가기
In vitro testing of salt coating of fabrics as a potential antiviral agent in reusable face masksArticle Published on 2022-10-112022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 치료제, [키워드] added airway Antiviral cloth mask cloth masks collected conditions coronavirus disease COVID-19 cultures dependent on dilutions distribution Effectiveness eight epithelia epithelial evaluated Face mask Face masks H3N2 handling incubated mandatory Masks pandemic protocol quantified reduced relative remained risk Sodium chloride tested turn viral replication virus particle virus replication wearing face mask [DOI] 10.1038/s41598-022-21442-7 PMC 바로가기
Imbalanced Angiogenesis in Pregnancies Complicated by SARS-CoV-2 InfectionArticle Published on 2022-10-072022-11-15 Journal: Viruses [Category] COVID19(2023년), SARS, 바이오마커, [키워드] Admission age angiogenic factors antithrombotic therapy Asymptomatic asymptomatic patient clinically collected COVID-19 cut-off value death diagnosed Diagnosis diagnosis of SARS-CoV-2 dysfunction dysregulation endothelial Endothelial dysfunction evaluate Factors FGR gestation growth factor hospital incidence Infection intensive care management marker mother Neonatal Neonate not significantly different Patient placental placental dysfunction preeclampsia Pregnancy pregnant population pregnant women proportion RAS reported resulting Retrospective analysis SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 positive asymptomatic Serum level severity sFlt-1 Stillbirth stratified Symptom symptomatic symptomatic patient symptoms of COVID-19 turn tyrosine was performed with COVID-19 women [DOI] 10.3390/v14102207 PMC 바로가기
Artificial Neural Network-Based Study Predicts GS-441524 as a Potential Inhibitor of SARS-CoV-2 Activator Protein Furin: a Polypharmacology ApproachArticle Published on 2022-10-012022-11-15 Journal: Applied biochemistry and biotechnology [Category] COVID19(2023년), SARS, 신약개발, 치료제, [키워드] activator ANN Antiviral antiviral drug antivirals artificial Bacterial Bacterial infection Cancer caused Compound COVID-19 diabetes DNA drug Drug repurposing ENhance FCGR1A FDA furin furin cleavage site Grazoprevir GS-441524 help human protein inhibit inhibiting inhibitor inhibitors LB-VS LDLR mammalian MK-5172 network pharmacology Neural Neurological disorders pandemic Patient PCK1 PNP polybasic Polypharmacology Potential researcher SARS-CoV-2 SB-VS searched SOM. substrate target the spike protein TLR7 turn Virtual screening virus [DOI] 10.1007/s12010-022-03928-2 PMC 바로가기
An integrated understanding of the evolutionary and structural features of the SARS-CoV-2 spike receptor binding domain (RBD)Article Published on 2022-09-302022-11-16 Journal: International journal of biological macromolecules [Category] COVID19(2023년), SARS, 변종, [키워드] Analysis binding Clustering co-evolution Computational drug conformational flexibility Conventional COVID-19 Critical deep Deep mutation scan develop drug-target druggability Effect Evolution expected exploratory feature Fuzzy C-means clustering highlight impair Interaction machine machine learning molecular dynamic simulation Molecular simulation Mutation network analysis Protein Quantitative RBD Receptor binding domain Region SARS-CoV-2 sequence Sequence space analysis small molecule stability Structure Structure network analysis. the RBD the SARS-CoV-2 turn [DOI] 10.1016/j.ijbiomac.2022.07.022 PMC 바로가기