Repurposing FDA-approved drugs against multiple proteins of SARS-CoV-2: An in silico study
Research article
[키워드] 3CLpro
ACE2
ADP
approach
approved drug
binding
binding energy
clinical study
complexes
Compound
Control
COVID-19
COVID-19 pandemic
Discovery Studio
docked
drug
Drug repurposing
drug target
DrugBank
drugs
Effectiveness
enzyme
ethynodiol
FDA
FDA-approved drug
food
greater
in silico
In silico methods
less
Ligand
Lopinavir
lower binding energy
lowest
molecular weight
phosphatase
protease
Protein
Proteins
ranged
RdRP
replicase
repurposing
RNA
RNA binding protein
RNA polymerase
SARS CoV-2
screened
target proteins
Target-based docking
the disease
therapeutic drug
UCSF Chimera
virus
were used
Withdrawal
[DOI] 10.1016/j.sciaf.2021.e00845 [Article Type] Research article
[DOI] 10.1016/j.sciaf.2021.e00845 [Article Type] Research article