The Application of Newcastle Disease Virus (NDV): Vaccine Vectors and Tumor TherapyReview Published on 2024-05-302024-09-05 Journal: Viruses [Category] update2024, [키워드] newcastle disease virus tumor therapy vaccine vector [DOI] 10.3390/v16060886 PMC 바로가기 [Article Type] Review
Oral Administration of Universal Bacterium-Vectored Nucleocapsid-Expressing COVID-19 Vaccine is Efficacious in Hamstersarticle Published on 2023-03-142024-09-05 Journal: Microbiology Spectrum [Category] update2024, [키워드] bacterial vector COVID-19 membrane protein mouse nucleocapsid protein oral administration Oral vaccine SARS-CoV-2 single vector platform single vector platform vaccine Syrian hamster Vaccine vaccine vector [DOI] 10.1128/spectrum.05035-22 PMC 바로가기 [Article Type] article
Modular capsid decoration boosts adenovirus vaccine-induced humoral immunity against SARS-CoV-2Article Published on 2022-12-072023-07-10 Journal: Molecular therapy : the journal of the American So [Category] COVID19(2023년), [키워드] Adenovirus protein superglue SARS-CoV-2 vaccine vector vector engineering. [DOI] 10.1016/j.ymthe.2022.08.002 PMC 바로가기
MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination전장 바이러스 단백질을 발현하는 MCMV 기반 백신 벡터는 단회 백신 접종 시 장기간 체액성 면역 보호를 제공합니다Article Published on 2022-01-072022-09-12 Journal: Cellular and Molecular Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome antigenic peptide caused CD8 Cellular immune response cellular immunity clinically CMV coronavirus cytomegalovirus Effect elicit excluded expressing full-length humoral humoral imunity Humoral response immune protection immune response Immunological memory induce Influenza influenza A virus Influenza virus injection investigated medical need memory T cells mice morbidity and mortality murine neutralizing antibody responses Pandemics Pathogens Population Protective Protein public health Respiratory pathogens robust SARS-CoV-2 T cell the spike protein vaccination Vaccine vaccine vector Vaccines vector Viral protein [DOI] 10.1038/s41423-021-00814-5 PMC 바로가기 [Article Type] Article
A single intranasal dose of a live-attenuated parainfluenza virus-vectored SARS-CoV-2 vaccine is protective in hamsters생약독화 파라인플루엔자 바이러스 매개 SARS-CoV-2 백신의 단일 비강 투여는 햄스터를 보호합니다423 Published on 2021-12-072022-09-12 Journal: Proceedings of the National Academy of Sciences of [Category] Coronavirus, SARS, 진단, [키워드] age all age groups antibody Antigen B.1.1.7 B.1.351 children chimeric clinical evaluation contribute COVID-19 dose effort evaluated exhibited Express expressed expressing expression fold generally mild hamster hamsters IgA IgG immunization immunogenic Infant Infants intranasal intranasal immunization intranasally Lineage lineages lung Lungs manuscript moderate morbidity nasal tissue neutralization Neutralizing activity parainfluenza parainfluenza virus parainfluenza virus 3 parainfluenza virus vaccines pediatric prefusion PROTECT Protective Receptor binding domain replicated Replication respiratory tract restrict robust S protein S-2P SARS-CoV-2 SARS-CoV-2 infections SARS-CoV-2 replication SARS-CoV-2 S SARS-CoV-2 S protein SARS-CoV-2 vaccine SARS-CoV-2 vaccines serum Significance significantly higher Single-dose Spike protein TCID the SARS-CoV-2 titers Transmission dynamics undetectable Vaccine vaccine candidate vaccine vector vector vectors virus was reduced weight loss [DOI] 10.1073/pnas.2109744118 PMC 바로가기 [Article Type] 423
Immunogenicity and efficacy of the COVID-19 candidate vector vaccine MVA-SARS-2-S in preclinical vaccination코로나19 후보 벡터백신 MVA-SARS-2-S의 전임상 접종에서 면역원성과 효능423 Published on 2021-07-132022-09-10 Journal: Proceedings of the National Academy of Sciences of [Category] SARS, 비임상, 진단, [키워드] acute respiratory syndrome Adenovirus Administered Antigen approved binding breath candidate vaccine cause CD8 cellular Characteristics children clinical evaluation clinical experience clinical trial component consequence coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccines disease Ebola virus disease economics Efficacy expresse expressing expression full-length SARS-CoV-2 growth Health heterologous prime-boost homologous Human human ACE2 Humoral immunity immunization immunocompromised individuals immunogenicity Infection infectious agent intramuscular investigated MERS-CoV mice Middle East Middle East respiratory syndrome Coronavirus modified vaccinia virus neutralized nonclinical testing pandemic coronavirus Phase I poxvirus produced Protective Protein reached resource respiratory respiratory syndrome coronavirus robust S protein Safe SARS-CoV-2 SARS-COV-2 infection serum antibodies serum antibody Severe acute respiratory syndrome Significance smallpox vaccine stability T cell T cells vaccination Vaccine vaccine vector vaccinia virus vector Virus Disease [DOI] 10.1073/pnas.2026207118 PMC 바로가기 [Article Type] 423
Understanding Post Entry Sorting of Adenovirus Capsids; A Chance to Change Vaccine Vector Properties아데노 바이러스 캡시드의 입력 후 분류 이해;백신 벡터 특성을 변경할 수있는 기회Review Published on 2021-06-242022-09-10 Journal: Viruses [Category] MERS, SARS, 비임상, [키워드] Adaptive immunity Adenovirus Affect approach autophagy breath chance change characterized choice effort feature focus Genetic Genotype genotypes Health Health crisis Immunity immunogenic IMPROVE include influence Innate immunity intracellular trafficking membrane outcomes Particle pathogenic property Protein SARS-CoV-2 serotype sorting stability subcellular subsequent the SARS-CoV-2 translate understanding Vaccine vaccine vector vector viral capsid virus entry [DOI] 10.3390/v13071221 PMC 바로가기 [Article Type] Review
Sendai Virus-Vectored Vaccines That Express Envelope Glycoproteins of Respiratory VirusesReview Published on 2021-05-292022-10-28 Journal: Viruses [Category] COVID-19, [키워드] Adults African green monkeys age assist attachment protein B-cell cause children clinical Collaborative effort envelope envelope glycoprotein fusion glycoprotein glycoprotein hRSV Human immunopathology Immunosuppression India individual induce Infant Infection métapneumovirus mucosal parainfluenza parainfluenza virus paramyxovirus pediatric Phase I pneumovirus PROTECT respiratory Respiratory disease respiratory syncytial virus Sendai virus SeV T-cell immune response Trial Vaccine vaccine vector Vaccines viral disease viral glycoprotein virus [DOI] 10.3390/v13061023 PMC 바로가기 [Article Type] Review
An overview of chitosan and its application in infectious diseasesOriginal Article Published on 2021-01-262023-06-17 Journal: Drug delivery and translational research [Category] MERS, [키워드] chitosan Infectious disease nanoparticle vaccine vector Wound dressing [DOI] 10.1007/s13346-021-00913-w PMC 바로가기 [Article Type] Original Article
[The Challenges of Vaccine Development Against Betacoronaviruses: Antibody Dependent Enhancement and Sendai Virus as a Possible Vaccine Vector]Review Published on 2020-11-012023-07-12 Journal: Molekuliarnaia biologiia [Category] SARS, [키워드] ADE Antibody-dependent enhancement conservative antigenic determinants COVID-19 murine respirovirus SARS-CoV-1 SARS-CoV-2 Sendai virus vaccine vector [DOI] 10.31857/S0026898420060154 [Article Type] Review