The protective effect of natural medicines in rheumatoid arthritis via inhibit angiogenesisPharmacology Review Published on 2024-05-312024-09-05 Journal: Frontiers in Pharmacology [Category] update2024, [키워드] Angiogenesis Ingredients mechanisms natural medicines rheumatoid arthritis VEGF [DOI] 10.3389/fphar.2024.1380098 PMC 바로가기 [Article Type] Pharmacology Review
A rapid VEGF-gene-sequence photoluminescence detector for osteoarthritisarticle Published on 2024-02-062024-09-05 Journal: Frontiers in Bioengineering and Biotechnology [Category] update2024, [키워드] CRISPR/Cas12a Mn-ZIF Osteoarthritis Photoluminescence VEGF [DOI] 10.3389/fbioe.2024.1338901 PMC 바로가기 [Article Type] article
New Avenues to Explore in SARS-CoV-2 Infection: Both TRIM25 and TRIM56 Positively Correlate with VEGF, GAS6, and sAXL in COVID-19 PatientsArticle Published on 2022-12-012023-07-10 Journal: Viral immunology [Category] COVID19(2023년), [키워드] GAS6 HIF-1α sAXL. TRIM25 TRIM56 VEGF [DOI] 10.1089/vim.2022.0112
Randomized, double-blind, placebo-controlled, crossover trial of oral doxycycline for epistaxis in hereditary hemorrhagic telangiectasiaArticle Published on 2022-11-072022-11-16 Journal: Orphanet Journal of Rare Diseases [Category] 유전자 메커니즘, [키워드] Analysis Angiogenesis assigned Biomarkers bleeding Blood center double-blind doxycycline Effectiveness ENG Epistaxis Frequency heart failure help hemorrhage Hemorrhagic Hereditary Hereditary hemorrhagic telangiectasia Hereditary hemorrhagic telangiectasia. HHT IL-6 Inflammatory intravenous limitations Liver disease malformation marker mechanism Michael morbidity no significant difference not significantly different observation pathway Patient Placebo placebo-controlled provided Quality of life Randomized controlled trial Randomly RBC recruited Registered Registration secondary significantly higher stroke telangiectasia therapy Toronto Treatment treatment period Trial VEGF [DOI] 10.1186/s13023-022-02539-8 PMC 바로가기
Acute kidney injury associated to COVID-19 leads to a strong unbalance of circulant immune mediatorsCOVID-19와 관련된 급성 신장 손상은 순환 면역 매개체의 강한 불균형으로 이어집니다Article Published on 2022-09-012022-09-12 Journal: Cytokine [Category] COVID19(2023년), MERS, SARS, 바이오마커, 진단, 치료기술, [키워드] accompanied Acute kidney injury AKI AKI patient AKI patients alteration analyzed association CCL-2 CCL-3 clinical outcomes contribute coronavirus disease COVID-19 COVID-19 patient CXCL-10 CXCL-8 Cytokines death demonstrated diabete Follow-up Frequency hospital discharge hospitalized patient IFN-γ IL-10 IL-2 IL-6 immune Immune mediators. immune response immunoassay immunopathological increased risk investigated kidney Kidney injury male moderate multiplex Patient performed Predictive ROC Curve SARS-CoV-2 viral load severe COVID-19 significantly significantly higher sustained the disease timepoint TNF-α VEGF Viral load were measured [DOI] 10.1016/j.cyto.2022.155974 PMC 바로가기 [Article Type] Article
SARS-CoV-2 infection- induced growth factors play differential roles in COVID-19 pathogenesisSARS-CoV-2 감염 유발 성장 인자는 COVID-19 발병 기전에서 다른 역할을 합니다Article Published on 2022-09-012022-09-11 Journal: Life sciences [Category] COVID19(2023년), MERS, SARS, 바이오마커, 치료기술, [키워드] adverse effect adverse effects angiopoietin association COVID-19 COVID-19 pathogenesis COVID-19 patient Critical Critically ill cytokine Cytokine storm Cytokine storms Cytokines D-dimer disease dysregulation EGF elevated Endothelial dysfunction EPO erythropoietin exhibited G-CSF growth factor Growth factors HGF Hospitalized ICU Inflammation Injury inverse correlation investigation marker moderate Myoglobin negative correlation non-ICU occur P-selectin Pathogenesis pathogenesis of COVID-19 pathophysiology PDGF plasma positive correlation reflected remained repair SARS-COV-2 infection selectin specific disease Thromboembolism tissue tissue injury Tissue injury. upregulated vague VEGF was performed [DOI] 10.1016/j.lfs.2022.120703 PMC 바로가기 [Article Type] Article
Eosinopenia and increased markers of endothelial damage are characteristic of COVID-19 infection at time of hospital admissionArticle Published on 2022-07-012023-07-09 Journal: Scandinavian journal of clinical and laboratory in [Category] COVID19(2023년), [키워드] COVID-19 Endothelin Eosinopenia SARS-CoV-2 smooth muscle autoantibodies. VCAM VEGF [DOI] 10.1080/00365513.2022.2079095
Potential Material Basis of Yupingfeng Powder for the Prevention and Treatment of 2019 Novel Coronavirus Pneumonia: A Study Involving Molecular Docking and Molecular Dynamic Simulation Technology2019년 신종 코로나바이러스 폐렴의 예방 및 치료를 위한 Yupingfeng 분말의 잠재적 재료 기반: 분자 도킹 및 분자 동적 시뮬레이션 기술 관련 연구Article Published on 2022-06-242022-09-11 Journal: BioMed Research International [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] 2019 novel coronavirus 2019 novel coronavirus pneumonia Algorithm Analysis analyzed AutoDock Basis binding Chinese common disease complexes component Coronavirus pneumonia Cytoscape software database disease DisGeNET docking dynamic enrichment analysis free energy Free energy calculation Free energy calculations Gene ontology GeneCard generate HIF-1 hydrogen Hydrogen bond identify ingredient Interaction investigated Involving KEGG pathway MAPK material mechanism molecular molecular docking molecular dynamic simulations novel Novel coronavirus novel coronavirus pneumonia Pathways performed Pneumonia Potential potential mechanism powder predict Predictive prevention protease Protein protein-protein interaction receptor retrieved SARS-CoV-2 selected Simulation STRING database T cell T cell receptor target target gene Target genes TCMSP technology TNF Toll-like receptor Topology Traditional Chinese medicine Treatment VEGF VEGF signaling was used were used [DOI] 10.1155/2022/7892397 PMC 바로가기 [Article Type] Article
Identification of bronchoalveolar and blood immune-inflammatory biomarker signature associated with poor 28-day outcome in critically ill COVID-19 patients중환자 COVID-19 환자에서 좋지 않은 28일 결과와 관련된 기관지 폐포 및 혈액 면역 염증 바이오마커 식별Article Published on 2022-06-092022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 바이오마커, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission assays BAL BAL fluid BALF Biological biological profile biomarker signature Blood blood concentration bronchoalveolar Bronchoalveolar lavage Characteristics clinical Clinical outcome Concentration coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients Critical Critically ill critically ill COVID-19 patients Critically ill patient critically ill patients cytokine defined described eicosanoid Eicosanoids elicited ELISA endothelial injury exhibited fiberoptic bronchoscopy Health Organization identification IFN-γ IL-10 IL-22 IL-5 IL-6 Infection Inflammatory response intensive care intensive care unit interferon Local metabolomic analysis neutrophil outcome Patient performed phenotype respiratory SARS-CoV-2 scale severe acute respiratory syndrome Coronavirus type I interferon Vascular Vasoactive VEGF WHO-CPS World Health Organization [DOI] 10.1038/s41598-022-13179-0 PMC 바로가기 [Article Type] Article
Long-term impact of delayed follow-up due to COVID-19 lockdown on patients with neovascular age-related macular degeneration신생혈관성 연령 관련 황반변성 환자에 대한 COVID-19 잠금으로 인한 지연된 추적관찰의 장기적인 영향Article Published on 2022-05-202022-09-12 Journal: BMC ophthalmology [Category] MERS, 진단, [키워드] accelerated age Age-related macular degeneration Analysis anti-vascular Anti-vascular endothelial growth factor (anti-VEGF) Anti-VEGF anti-VEGF treatment association Care clinical trial coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 COVID-19 pandemic database detrimental distance endothelial female First wave Follow-up growth factor Health Intervention intravitreal injection lockdown Loss male median Missed Neovascular age-related macular degeneration (nAMD). no correlation Optical coherence tomography outcome pandemic Patient patients Predictive progression reduced reduction Registered regression analysis Retrospective study significantly significantly increased treated Treatment VEGF visual acuity was performed were assessed [DOI] 10.1186/s12886-022-02453-4 PMC 바로가기 [Article Type] Article