An engineered 5-helix bundle derived from SARS-CoV-2 S2 pre-binds sarbecoviral spike at both serological- and endosomal-pH to inhibit virus entrySARS-CoV-2 S2에서 파생된 조작된 5나선 번들은 바이러스 진입을 억제하기 위해 혈청학적 pH와 엔도솜 pH 모두에서 사베코바이러스 스파이크를 사전 결합합니다.Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] [DOI] 10.1080/22221751.2022.2095308 PMC 바로가기 [Article Type] Article
Broad Tricyclic Ring Inhibitors Block SARS-CoV-2 Spike Function Required for Viral EntryArticle Published on 2022-10-142022-11-16 Journal: ACS Infectious Diseases [Category] [DOI] 10.1021/acsinfecdis.1c00658 PMC 바로가기
The Spike-Stabilizing D614G Mutation Interacts with S1/S2 Cleavage Site Mutations To Promote the Infectious Potential of SARS-CoV-2 VariantsArticle Published on 2022-10-122022-11-16 Journal: Journal of Virology [Category] [DOI] 10.1128/jvi.01301-22 PMC 바로가기
Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike proteinArticle Published on 2022-10-042022-11-15 Journal: Proceedings of the National Academy of Sciences of [Category] [DOI] 10.1073/pnas.2210990119 PMC 바로가기
Peimine inhibits variants of SARS-CoV-2 cell entry via blocking the interaction between viral spike protein and ACE2Article Published on 2022-10-012022-11-16 Journal: Journal of food biochemistry [Category] [DOI] 10.1111/jfbc.14354 PMC 바로가기
Molecular Analyses of Clinical Isolates and Recombinant SARS-CoV-2 Carrying B.1 and B.1.617.2 Spike Mutations Suggest a Potential Role of Non-Spike Mutations in Infection KineticsArticle Published on 2022-09-122022-11-15 Journal: Viruses [Category] [DOI] 10.3390/v14092017 PMC 바로가기
Immunomolecular assay based on selective virion capture by spike antibody and viral nucleic acid amplification for detecting intact SARS-CoV-2 particlesArticle Published on 2022-09-052022-11-15 Journal: Journal of Nanobiotechnology [Category] [DOI] 10.1186/s12951-022-01558-8 PMC 바로가기
Characterization of ACE2 naturally occurring missense variants: impact on subcellular localization and traffickingArticle Published on 2022-09-022022-11-16 Journal: Human Genomics [Category] [DOI] 10.1186/s40246-022-00411-1 PMC 바로가기
Comparison of commercial SARS-CoV-2 surrogate neutralization assays with a full virus endpoint dilution neutralization test in two different cohorts두 개의 다른 코호트에서 상용 SARS-CoV-2 대리 중화 분석과 전체 바이러스 종말점 희석 중화 테스트의 비교Article Published on 2022-09-012022-09-11 Journal: Journal of virological methods [Category] [DOI] 10.1016/j.jviromet.2022.114569 PMC 바로가기 [Article Type] Article
Highly restricted SARS-CoV-2 receptor expression and resistance to infection by primary human monocytes and monocyte-derived macrophages고도로 제한된 SARS-CoV-2 수용체 발현 및 1차 인간 단핵구 및 단핵구 유래 대식세포에 의한 감염에 대한 내성Article Published on 2022-09-012022-09-11 Journal: Journal of leukocyte biology [Category] [DOI] 10.1002/JLB.4COVA1121-579RR PMC 바로가기 [Article Type] Article