CoVITEST: A Fast and Reliable Method to Monitor Anti-SARS-CoV-2 Specific T Cells From Whole BloodCoVITEST: 전혈에서 Anti-SARS-CoV-2 특정 T 세포를 모니터링하는 빠르고 신뢰할 수 있는 방법Article Published on 2022-07-052022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] adjust antibodies Antibody detection automated Blood blood test can be used Cellular immune response cellular immunity cellular response comparable complex convalescent COVID-19 demonstrated determine diagnostic Donor ELISPOT Evidence explained gold gold standard healthy help house humoral immune response humoral immune responses IFN-γ IFN-γ ELISPOT immune protection immune responses Immune status IMPROVE individual less MONITOR pandemic Patient protocol Reinfection SARS-CoV-2 side simple Specific Support T cell T cells Test therapeutic approaches vulnerable patient vulnerable patients weakened immune system [DOI] 10.3389/fimmu.2022.848586 PMC 바로가기 [Article Type] Article
Immunogenicity of COVID-19 Vaccination in Melanoma Patients under Immune Checkpoint Blockade면역관문 봉쇄하에 있는 흑색종 환자에서 코로나19 예방접종의 면역원성Article Published on 2022-01-012022-09-12 Journal: Oncology [Category] SARS, 진단, [키워드] Advanced melanoma Analysis anti-SARS-CoV-2 spike protein antibody Antibody Response Blood cancer patient Care center comparable COVID-19 COVID-19 vaccination COVID-19 vaccine described ELISA ENhance expected Germany Hanover Health healthy humoral immune response IgG antibodies Immune checkpoint inhibitors immune response immunogenicity independent influenza vaccines inhibitor median Melanoma observé Patient professionals Quantitative recruited SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine significantly higher skin study population targeted therapy the timing therapy Treatment vaccination was performed weakened immune system [DOI] 10.1159/000524894 PMC 바로가기 [Article Type] Article
Rampant Increase in Cases of Mucormycosis in India and Pakistan: A Serious Cause for Concern during the Ongoing COVID-19 PandemicPerspective Piece Published on 2021-11-302022-10-28 Journal: The American Journal of Tropical Medicine and Hygi [Category] COVID-19, MERS, [키워드] cause Comorbidity concern COVID-19 COVID-19 pandemic COVID-19 patient Critical diabetes equipment Health highlight Implications increase increase in India intubation Mucormycosis oxygen pandemic reported steroid weakened immune system [DOI] 10.4269/ajtmh.21-0608 PMC 바로가기 [Article Type] Perspective Piece
Identifying Mucormycosis Severity in Indian COVID-19 Patients: A Nano-Based Diagnosis and the Necessity for Critical Therapeutic InterventionReview Published on 2021-10-272022-10-27 Journal: Antibiotics [Category] COVID-19, [키워드] Antifungal approach cause caused Clinical presentations condition connection cough COVID-19 COVID-19 epidemic COVID-19 infection diabetes Diagnosis diagnostic disorders early diagnosis fungal Fungal infection help hypertension identifying India individual information instance Intervention life-threatening Mild Mucormycosis Nanotechnology new SARS-CoV-2 parameters Pneumonia point-of-care tests Prevalence provide Recovered COVID-19 patients reduction in reported Research second wave severity spread of COVID-19 statistical surgical Symptoms the disease Therapies therapy Topic Treatment virus weakened immune system [DOI] 10.3390/antibiotics10111308 PMC 바로가기 [Article Type] Review
Doxycycline for community treatment of suspected COVID-19 in people at high risk of adverse outcomes in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial영국에서 역효과 위험이 높은 사람들을 대상으로 코로나19가 의심되는 지역사회 치료를 위한 독시사이클린(원칙): 무작위, 통제, 공개, 적응 플랫폼 시험Randomized Controlled Trial Published on 2021-09-012022-09-11 Journal: The Lancet. Respiratory Medicine [Category] Fulltext, SARS, 임상, 치료법, [키워드] absence adaptive Adaptive platform trial adaptive randomisation adverse outcome adverse outcomes age analysed assigned Asthma Bayesian BCI benefit body-mass body-mass index clinical trial clinical trials clinically Community Comorbidities Comorbidity contributed COVID-19 credible interval criterion death defined Department diabetes disease doxycycline Efficacy Endpoint enrolled Evidence evidence of female FIVE Follow-up greater groups hazard ratio heart disease hepatic impairment high risk Hospital admission Hospital admissions hospitalisation hypertension Innovation Intention intention to treat interval Intervention ISRCTN Lung disease male manuscript median time Mild multi-arm National neurological obesity occurred Older once daily Open-label participant participants randomly assigned Patient platform Platform trial positive PCR test primary analysis primary care principle Probability randomisation randomised Randomised trial Randomly reductions in Registered reported respiratory symptom respiratory symptoms SARS-COV-2 infection stroke Support the mean Time to recovery treat treating COVID-19 Treatment treatment for COVID-19 Trial usual care weakened immune system [DOI] 10.1016/S2213-2600(21)00310-6 PMC 바로가기 [Article Type] Randomized Controlled Trial
Evaluation of the efficacy and safety of recombinant erythropoietin on the improvement of hospitalised COVID-19 patients: A structured summary of a study protocol for a randomised controlled trial입원한 COVID-19 환자의 개선에 대한 재조합 에리트로포이에틴의 효능 및 안전성 평가: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-07-062022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 48 hours Adverse reaction Adverse reactions age approved Arm Bandar Abbas Blinding block randomization blood pressure Care checked chronic lung disease clinical clinical symptom clinical trial clinical trials Committee company comparator Patients composite endpoint control group Controlled clinical trial controls Coronary heart disease COVID-19 COVID-19 patient COVID-19 patients CRP Deep vein Deep vein thrombosis diabetes Diabetes Mellitus Diastolic blood pressure dissemination distilled water Efficacy and safety element End-stage renal disease endogenous enoxaparin erythropoietin ethics committee evaluate evaluate the effect excluded exclusion criteria expected Haemoglobin Health Health care heart disease hospitalised hospitalised COVID-19 patients Hypoxemia immune system infiltration injection intervals Intervention intervention group investigator Iran Laboratory test Laboratory tests LDH Liver disease Local Lung disease lung field lung infiltration lymphocyte Lymphocyte count lymphopenia Medical Science Medical Sciences medication minute number objective oral contraceptive outcome oxygen oxygen partial pressure oxygen saturation parallel-group partial pressure participant Patient PCR performed pharmaceutical Pharmaceutical Company Phase 2 Placebo positive Prevent principal investigator protocol randomised randomised controlled trial Randomized Randomly receive recombinant erythropoietin recruitment Registered registry renal disease reported respiratory respiratory rate Sample size saturation severe COVID-19 symptom severe COVID-19 symptoms Side effect Side effects Standard Standard of care status sterile water Study protocol subcutaneous injection subject supplementary material Systolic blood pressure tachypnea technology the ethics committee thrombosis title Treatment protocol treatment protocols Trial registration university vital signs water water for injection weakened immune system website [DOI] 10.1186/s13063-021-05363-w PMC 바로가기 [Article Type] Letter
Nanoscale pathogens treated with nanomaterial-like peptides: a platform technology appropriate for future pandemics나노물질과 같은 펩타이드로 치료된 나노규모 병원체: 미래 유행병에 적합한 플랫폼 기술Review Published on 2021-05-142022-09-10 Journal: Nanomedicine [Category] MERS, 치료제, [키워드] Abstract accompanied Antiviral antiviral drug antiviral peptides approach COVID-19 develop Healthcare system Infection MOST nanomaterials Nanoparticles Nanotechnology Pandemics pathogen peptides permission platform Therapeutic approach therapeutic approaches time-consuming treat treated Vaccine Viral viral infection viral infections virus viruses weakened immune system [DOI] 10.2217/nnm-2020-0447 PMC 바로가기 [Article Type] Review
Probabilities of ICU admission and hospital discharge according to patient characteristics in the designated COVID-19 hospital of KuwaitResearch Article Published on 2021-04-262022-10-28 Journal: BMC Public Health [Category] COVID-19, MERS, SARS, [키워드] absence Admission admitted to ICU age Analysis association Asthma Characteristics Chronic kidney disease chronic obstructive CKD Combination Comorbidities Comorbidity competing Competing risks conducted confirmed COVID-19 case country covariates COVID-19 Critical care curative demographics Describing discharge discharged effective epidemic wave Epidemiological study events examined female flexible Gender healthcare hospital Hospital admission hospital discharge hospital management ICU ICU admission increased the risk increasing age individual intensive care unit Jaber Al-Ahmad Al-Sabah Kuwait male moderate outcome Patient patients with COVID-19 positive positive COVID-19 prevalent Probability Probability of ICU admission prospective cohort study provide provided pulmonary disease Record recorded Result risk supplementary material symptomatic and asymptomatic tested transferred treated Vaccination strategy was performed weakened immune system [DOI] 10.1186/s12889-021-10759-z PMC 바로가기 [Article Type] Research Article
Fruits and Vegetables in the Management of Underlying Conditions for COVID-19 High-Risk GroupsReview Published on 2021-02-102022-11-01 Journal: Foods [Category] COVID-19, [키워드] boost cardiovascular diseases Cell Chronic kidney disease chronic obstructive condition coughing COVID-19 COVID-19 illness death diabetes diarrhea disease disorder early stage Factor fatigue Fever food handling food safety fruit fruits and vegetables group Headaches Health health benefits hemoglobin high risk immune system IMPROVE Infection lack limit loss of appetite loss of taste micronutrients Novel coronavirus obesity Organ transplant pandemic pulmonary disease quarantine risk robust SARS-CoV-2 Shortness of breath Symptom underlying condition underlying conditions vegetable virus vomiting weakened immune system [DOI] 10.3390/foods10020389 PMC 바로가기 [Article Type] Review
Nutritional status of micronutrients as a possible and modifiable risk factor for COVID-19: a UK perspectiveFull Papers Published on 2020-08-202022-10-28 Journal: The British Journal of Nutrition [Category] COVID-19, Fulltext, MERS, SARS, [키워드] 25(OH)D, 25-hydroxyvitamin D alcohol ARTI, acute respiratory tract infection benefit Care clinical settings co-morbidities contribute COVID-19 COVID-19 infection COVID-19 infections COVID-19 pandemic Critical darker skin deficiency Essential micronutrients essential nutrient Evidence Factor group help highlight immune functions immune system include increased risk indicated knowledge lack medications Micronutrient Minerals normal function obese Other Patient Perspective Population potential risk Prevent public health question recent reduce Resilience risk factor Risk factors smoking social distancing susceptible Transmission Vitamin vitamin A Vitamin C Vulnerable groups weakened immune system [DOI] 10.1017/S000711452000330X PMC 바로가기 [Article Type] Full Papers