Differences in virus and immune dynamics for SARS-CoV-2 Delta and Omicron infections by age and vaccination historiesResearch Published on 2024-06-292024-09-05 Journal: BMC Infectious Diseases [Category] update2024, [키워드] age Bayesian inference Immunity Mechanistic model modelling SARS-CoV-2 vaccination variants waning within-host [DOI] 10.1186/s12879-024-09572-x PMC 바로가기 [Article Type] Research
Within-host genomic evolution of methicillin-resistant Staphylococcus aureus in long-term carriersGenomics, Transcriptomics, Proteomics Published on 2024-01-112024-09-05 Journal: Applied Microbiology and Biotechnology [Category] update2024, [키워드] cgMLST genomic evolution MRSA Recombination SNP within-host [DOI] 10.1007/s00253-023-12932-3 PMC 바로가기 [Article Type] Genomics, Transcriptomics, Proteomics
Assessing the hidden diversity underlying consensus sequences of SARS-CoV-2 using VICOS, a novel bioinformatic pipeline for identification of mixed viral populationsArticle Published on 2023-02-012023-07-11 Journal: Virus research [Category] COVID19(2023년), [키워드] Coinfection Evolution Intra-host SARS-CoV-2 virus within-host [DOI] 10.1016/j.virusres.2022.199035 PMC 바로가기
Variant-specific SARS-CoV-2 within-host kinetics변이체 특이적 SARS-CoV-2 숙주 내 역학Article Published on 2022-08-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] alpha and delta variants Alpha variant Analysis caused Chain Reaction characterized Cohort contagiousness copy number Ct values cycle threshold ddPCR Delta determinant digital PCR Epidemic epidemiological Evidence France General population highlight hospital individual Infection Kinetics lineages no significant difference Older performed polymerase chain polymerase chain reaction populations Quantitative RT-qPCR SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV2 screening test significant difference significantly higher Swab translate Transmission upper respiratory tract variant variant of concern variants variations viral dynamics viral genome virus virus load VoC VOCs within-host [DOI] 10.1002/jmv.27757 PMC 바로가기 [Article Type] Article
Mathematical models for dengue fever epidemiology: A 10-year systematic review뎅기열 역학에 대한 수학적 모델: 10년 체계적 고찰Review Published on 2022-03-012022-09-12 Journal: Physics of life reviews [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] ADE analyzed antibody Antibody dependent-enhancement Antibody-dependent enhancement approach Asymptomatic caused complex Consensus contribute COVID-19 pandemic Dengue Dengue fever DENV-1 DENV-4 described disease ENhance epidemiological Epidemiology Factor feature Fever identify immune response immunological Immunological response imperative Infection Infectious disease international public health mathematical mathematical model Mathematical models Mild Multi-strain not neutralize parameter problems progressed public health public health authority Research risk serotype severe disease systematic review the disease Transmission dynamics Transmission model Vector-host viral replication within-host [DOI] 10.1016/j.plrev.2022.02.001 PMC 바로가기 [Article Type] Review
Differential drivers of intraspecific and interspecific competition during malaria-helminth co-infectionarticle Published on 2021-08-312024-09-01 Journal: Parasitology [Category] 말라리아, [키워드] Co-infection dose dependence Hookworm infectious dose malaria within-host [Article Type] article
Patterns of within-host genetic diversity in SARS-CoV-2SARS-CoV-2의 숙주 내 유전적 다양성 패턴Research Article Published on 2021-08-132022-09-10 Journal: eLife [Category] MERS, SARS, 변종, 치료기술, [키워드] accumulation addition allele frequencies allele frequency analyses Analysis caution Co-infection consensus genome convergent evolution COVID-19 pandemic damage detectable determine develop Diversity driving eLife epidemiological Evolution example Factor focus genetic code genetic diversity genetic material Genetic testing genetic tests genetics globe Government Health help homoplasies Host hosts identify Impact individual individuals infected individuals Infection information Intervention Lineage MONITOR monitoring mutate Mutation mutation rate mutational hotspot Mutational hotspots mutational spectrum mutations Nonsense mutations occurred Other pandemic pattern Phylogenetic predict Prevent public health Recombination reconstruction Recurrent Replication responsible RNA SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 pandemic SARS-CoV-2 virus SARS-CoV-2 viruses Scientific community sequenced Sequencing Spectrum Spread spreads strain superinfection the SARS-CoV-2 the SARS-CoV-2 genome Transmission transmission of SARS-CoV-2 Vaccines variant variants Viral viral samples virus viruses while within-host [DOI] 10.7554/eLife.66857 PMC 바로가기 [Article Type] Research Article
A model of the innate immune response to SARS-CoV-2 in the alveolar epitheliumMathematics Published on 2021-08-112022-10-28 Journal: Royal Society Open Science [Category] COVID-19, [키워드] ACE2 expression alveolar epithelial cells alveolar epithelium antiviral therapy basic reproductive number benefit binding affinity Cell chemokines Control Course deleterious effect determinant epithelial exacerbate host response Impact individual variation Infection Innate immune cells innate immune response interferon interferons Model moderate parameters predicted Prognosis reduce robust SARS-CoV-2 SARS-CoV-2 spike protein significantly suppresse Therapies therapy tissue damage toxin type I Variability viral dynamics Viral load while within-host [DOI] 10.1098/rsos.210090 PMC 바로가기 [Article Type] Mathematics
Uncovering the effects of heterogeneity and parameter sensitivity on within-host dynamics of disease: malaria as a case study질병의 숙주 내 역학에 대한 이질성 및 매개변수 민감도의 영향 발견: 사례 연구로서의 말라리아Research Published on 2021-07-242024-07-27 Journal: BMC Bioinformatics [Category] 말라리아, [키워드] malaria modelling sensitivity analysis within-host [DOI] 10.1186/s12859-021-04289-z PMC 바로가기 [Article Type] Research
Beyond Infection: Integrating Competence into Reservoir Host PredictionArticle Published on 2020-12-012023-06-14 Journal: Trends in ecology & evolution [Category] Fulltext, 조류인플루엔자, [키워드] machine learning SARS-CoV-2 Vector-borne disease within-host zoonoses [DOI] 10.1016/j.tree.2020.08.014 PMC 바로가기