Infections due to Salmonella sp. in children with chronic granulomatous disease: Our experience from North Indiaarticle Published on 2023-10-312024-09-01 Journal: Clinical Immunology [Category] 살모넬라증, [키워드] Bacteremia Chronic granulomatous disease Salmonella Vaccine X-linked [Article Type] article
Clinical implications of host genetic variation and susceptibility to severe or critical COVID-19심각하거나 치명적인 COVID-19에 대한 숙주 유전자 변이 및 감수성의 임상적 의미Review Published on 2022-08-192022-09-11 Journal: Genome Medicine [Category] SARS, 변종, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 advanced age age allergy Asymptomatic disease clinical clinical implications Clinical management clinical picture Comorbidities convergence coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Critical deficiency develop Effects expected Factor Genetic genetic finding genetic screening Genetic variant Genetic variation healthy individual heterogeneous Host host genetics human immune response IFN-I Immunity implication indicate Infectious disease interferon Male sex malignancies manifestation Mendelian disorder Mendelian disorders modulate pandemic pathogenic variant pathway Pathways Patient Pneumonia predisposition Prevalence rare variant Rare variants risk factor SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe manifestations of COVID-19 shown susceptibility susceptibility loci the interferon TLR7 virus X-linked [DOI] 10.1186/s13073-022-01100-3 PMC 바로가기 [Article Type] Review
Epigenetic mechanisms regulate sex-specific bias in disease manifestations후성 유전적 메커니즘은 질병 발현에서 성별에 따른 편향을 조절합니다Review Published on 2022-08-012022-09-11 Journal: Journal of Molecular Medicine (Berlin, Germany) [Category] 유전자 메커니즘, [키워드] affecting Anatomy Autoimmune disorders Cancer change chromosome Clinical outcome clinical study COVID-19 COVID-19 infection differential expression disease disease manifestation disease onset Diseases Effect Epigenetic epigenetic modification epigenetics exhibit explained expression fibrosis Genes Genetic Genetic and epigenetic changes Hormones immune response immune responses immune system implicated inactivation infections input involved Liver fibrosis mechanism Neuropsychiatric Neuropsychiatric diseases progression recent regulate Respiratory disease respiratory diseases response to therapy responsible Sex Sex bias Sex chromosome sex hormone Sex hormones susceptibility therapeutic targets therapy underlying disease X chromosome X-inactivation X-linked X-linked gene X-linked genes. [DOI] 10.1007/s00109-022-02227-x PMC 바로가기 [Article Type] Review
Responses to SARS-CoV-2 Vaccines of Patients with Common Variable Immune Deficiencies and X-linked Agammaglobulinemia공통 가변 면역 결핍증 및 X-연관 무감마글로불린혈증 환자의 SARS-CoV-2 백신에 대한 반응Article Published on 2022-07-012022-09-12 Journal: Journal of Clinical Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] agammaglobulinemia common response SARS-CoV-2 variable X-linked [DOI] 10.1007/s10875-022-01251-3 PMC 바로가기 [Article Type] Article
The Robustness of Cellular Immunity Determines the Fate of SARS-CoV-2 Infection세포 면역의 견고함이 SARS-CoV-2 감염의 운명을 결정합니다Review Published on 2022-06-272022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료제, [키워드] addition Administered Analysis antibody secreting cells antiviral cytokine antiviral cytokines antiviral immunity antiviral response appearance approach autosomal recessive axis B cell booster dose breadth CD4+ CD4+ T cell CD8+ Cell cellular Cellular immune response cellular immunity component contribute coordinating correlated COVID-19 COVID-19 patient Critical cross-protection Cytokines cytotoxic lymphocytes cytotoxic T lymphocytes described disease Disease progression disease severity dysregulated evasion Evolution follicular functional Germinal center global pandemic greater helper T cells humoral IFN-γ immune protection immune system Immunity in some infected cells Infection infection control inflammatory cascade innate immune system killing knowledge long-lasting lymphocyte Lymphocytes magnitude memory modulating neutralizing antibody pathogenic inflammation phenotypic pro-inflammatory cytokine pro-inflammatory cytokines protective immunity reported responsible robustness SARS-CoV-2 SARS-CoV-2 virus secreting severe COVID-19 severity Stage stages T cell T cell response T cell responses T cells T helper cell T helper cells Tfh Tfh cells the SARS-CoV-2 virus thought TNF-α vaccination Vaccine viral replication X-linked [DOI] 10.3389/fimmu.2022.904686 PMC 바로가기 [Article Type] Review
Features of Hemophagocytic Lymphohistiocytosis in Infants With Severe Combined Immunodeficiency: Our Experience From Chandigarh, North IndiaArticle Published on 2022-06-232023-06-14 Journal: Frontiers in Immunology [Category] Fulltext, 신종인플루엔자, [키워드] BCG family history hemophagocytic lymphohistiocytosis infections severe combined immunodeficiency X-linked [DOI] 10.3389/fimmu.2022.867753 PMC 바로가기
Case Report: X-Linked SASH3 Deficiency Presenting as a Common Variable Immunodeficiency증례 보고서: 공통 변수 면역 결핍으로 나타나는 X-연관 SASH3 결핍Case Reports Published on 2022-04-082022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, [키워드] age Autoimmune B cell bilateral pneumonia CD4 CD8 cells combined immunodeficiency common common variable immunodeficiency CVID deficiency described diagnosed dysregulation elevated Genetic testing genetics Haemophilus influenzae Haemophilus influenzae type b humans IgG and IgM immune dysregulation Immunity immunodeficiency immunological phenotype Inborn errors inborn errors of immunity Infection infections Influenza influenza infection loss-of-function lymphopenia memory B cells mucosal Mutation naïve T cells Patient patients phenotype polysaccharide primary immunodeficiencies. proliferation Protein reduced reported RNA SARS-CoV-2 SASH3 SASH3 deficiency Signaling Streptococcus pneumoniae survival T cell T cell activation T cells T-cell TCR Vaccine variable variant varicella Varicella zoster virus viral infection viral infections virus X-linked [DOI] 10.3389/fimmu.2022.881206 PMC 바로가기 [Article Type] Case Reports
Do reduced numbers of plasmacytoid dendritic cells contribute to the aggressive clinical course of COVID-19 in chronic lymphocytic leukaemia?감소된 수의 형질세포양 수지상 세포가 만성 림프구성 백혈병에서 COVID-19의 공격적인 임상 경과에 기여합니까?Review Published on 2022-04-012022-09-11 Journal: Scandinavian journal of immunology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] agammaglobulinemia BTK Chronic lymphocytic leukaemia Clinical course CLL combating contribute COVID-19 dendritic cells Express haematological malignancies inhibitor interferon interferons IRF7 malignancies mechanism observations patients patients with haematological pDC pDCs plasmacytoid dendritic cell plasmacytoid dendritic cells reduced reduction in SARS-CoV-2 TLR7 Toll-like receptor toll-like receptor 7 type I interferons tyrosine X-linked X-linked agammaglobulinemia [DOI] 10.1111/sji.13153 PMC 바로가기 [Article Type] Review
Risk-focused differences in molecular processes implicated in SARS-CoV-2 infection: corollaries in DNA methylation and gene expressionSARS-CoV-2 감염과 관련된 분자 과정의 위험 중심적 차이: DNA 메틸화 및 유전자 발현의 결과Research Published on 2021-12-112022-09-11 Journal: Epigenetics & Chromatin [Category] SARS, 유전자 메커니즘, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Air pollutants airway epithelia Analysis ARRB2 association Asthma autosomal Bronchoalveolar lavage CA5B candidate gene changes in chronic conditions chronic obstructive COMT conducted COPD coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 susceptibility CpG data set Diagnosis diesel exhaust DNA methylation downloaded epithelia exaggerated immune response exhibited explain Exploratory analysis exposure to Factor female Gene Expression gene expression patterns Genes GEO GPX1 Health highlight HS6ST2 immune genes imperative implicated inactivation increased risk individual Infection infections investigated involved loci lung magnitude male molecular molecular association molecular associations molecular basis molecular pattern molecular patterns mRNA expression nasal Nicotine nicotine dependence nitrogen nitrogen dioxide NLRP2 outcomes portal PRIM2 profile Repository respiratory Respiratory conditions Respiratory disease respiratory tissue Result risk risk factor Risk factors SARS-CoV-2 SARS-COV-2 infection second severe acute respiratory syndrome Coronavirus Sex Sex difference Smokers smoking suggested supplementary material susceptibility TATDN1 the disease TLE1 understanding Variation while Whole blood X-linked X-linked gene [DOI] 10.1186/s13072-021-00428-1 PMC 바로가기 [Article Type] Research
SARS-CoV-2 Infection in an Adolescent With X-linked AgammaglobulinemiaX-연관 무감마글로불린혈증이 있는 청소년의 SARS-CoV-2 감염Case Reports Published on 2021-12-012022-09-11 Journal: The Pediatric Infectious Disease Journal [Category] SARS, 바이오마커, 진단, 치료기술, 치료제, [키워드] acute infection Adolescent agammaglobulinemia Bronchoalveolar lavage change chest scan Course COVID-19 disease erythrocyte sedimentation erythrocyte sedimentation rate febrile Fever fevers high resolution high resolution CT infected with SARS-CoV-2 Mild Mild disease Multiple Nasopharyngeal swab nasopharyngeal swabs raised Remdesivir resolved respiratory respiratory symptoms RT-PCR SARS-CoV-2 sedimentation rate X-linked X-linked agammaglobulinemia [DOI] 10.1097/INF.0000000000003360 PMC 바로가기 [Article Type] Case Reports