COVID-19 vaccine rumors and conspiracy theories: The need for cognitive inoculation against misinformation to improve vaccine adherence코로나19 백신 루머와 음모론: 백신 순응도 향상을 위한 잘못된 정보에 대한 인지 접종의 필요성Research Article Published on 2021-05-122022-08-13 Journal: PLoS ONE [Category] COVID-19, Medicine and Health Sciences, SARS, [키워드] acceptance agency Analysis analyzed articles assist candidate categories check circulating cognitive conducted contribute contributing to COVID-19 COVID-19 vaccine disseminate Efficacy Facebook Fact false Google help IMPROVE information Intervention lead media misinformation monitoring morbidity morbidity and mortality Quantitative data Result rumor social media Source statistical Vaccine vaccine candidates Vaccine development Vaccine hesitancy YouTube [DOI] 10.1371/journal.pone.0251605 PMC 바로가기 [Article Type] Research Article
Multiplex qPCR discriminates variants of concern to enhance global surveillance of SARS-CoV-2Multiplex qPCR은 SARS-CoV-2의 글로벌 감시를 강화하기 위해 우려 변종을 식별합니다.Methods and Resources Published on 2021-05-072022-08-13 Journal: PLoS Biology [Category] Medicine and Health Sciences, SARS, 변종, 치료기술, 치료제, [키워드] 501Y.V1 501Y.V2 acute respiratory syndrome coronavirus B.1.1.7 B.1.351 Brazil can not circulating coronavirus coronavirus 2 COVID-19 Deletion detect ENhance escape gene target immune responses Laboratory lack lineages Local multiplex ORF1a other variant other variants P.1 PCR assay qPCR respiratory SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants Sequencing severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 South Africa Spread Surveillance TaqPath Thermo Fisher these viruses Transmissibility United Kingdom variant variants variants of concern viruses VoC [DOI] 10.1371/journal.pbio.3001236 PMC 바로가기 [Article Type] Methods and Resources
Prevalence and outcomes of co-infection and superinfection with SARS-CoV-2 and other pathogens: A systematic review and meta-analysisSARS-CoV-2 및 기타 병원체와의 동시 감염 및 중복 감염의 유병률 및 결과: 체계적인 검토 및 메타 분석Research Article Published on 2021-05-062022-08-13 Journal: PLoS ONE [Category] COVID-19, Medicine and Health Sciences, MERS, SARS, [키워드] 95% CI 95% confidence interval article average Bacterial bacterial superinfections clinical feature Clinical features Co-infection database Diagnosis diagnostic diagnostic testing fungal greater higher odd higher odds Hospital stay Hospitalized identify increased mortality Infection mechanical ventilation Meta-analysis Microbiology Occurrence Odds ratio outcome outcomes pathogen Pathogens Patient patients patients with COVID-19 patients with SARS-CoV-2 Prevalence PROSPERO protocol random effect Registered reported respiratory respiratory infection respiratory infections Result SARS-CoV-2 SARS-COV-2 infection screened searched Standard deviation stratified superinfection Support systematic review treat Viral [DOI] 10.1371/journal.pone.0251170 PMC 바로가기 [Article Type] Research Article
Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodiesACE2 및 2개의 강력한 중화 항체와 복합체를 이루는 N501Y SARS-CoV-2 스파이크 단백질의 저온 전자 현미경 구조Research Article Published on 2021-04-292022-08-13 Journal: PLoS Biology [Category] COVID-19, Medicine and Health Sciences, MERS, SARS, [키워드] ACE2 ACE2 receptor B.1.1.7 binding Cavity changes circulating complex contribute Cryo-electron microscopy cryo-EM cryo-EM structure cryo-EM structures ectodomain epitope Epitopes Interaction Microscopy mutant Mutation N501Y N501Y mutation neutralization neutralizing antibody provide Receptor binding domain reported retained SARS-CoV-2 SARS-CoV-2 spike protein Spike protein Spike receptor binding domain strain Structure thought [DOI] 10.1371/journal.pbio.3001237 PMC 바로가기 [Article Type] Research Article
COVID-19 and vaccine hesitancy: A longitudinal studyCOVID-19와 백신 망설임: 종단 연구Research Article Published on 2021-04-162022-08-13 Journal: PLoS ONE [Category] COVID-19, Medicine and Health Sciences, MERS, SARS, [키워드] asymmetric Behavior Course COVID-19 COVID-19 pandemic COVID-19 vaccination COVID-19 vaccine decrease disease driven by Evidence explain exposure to Health crisis heterogeneity identify IMPROVE indicated Influenza influenza vaccine Intention less media participant public health public health crisis remained Research Risk perception social networks United State United States vaccination Vaccine Vaccines virus [DOI] 10.1371/journal.pone.0250123 PMC 바로가기 [Article Type] Research Article
Partisanship, health behavior, and policy attitudes in the early stages of the COVID-19 pandemicCOVID-19 전염병 초기 단계의 당파성, 건강 행동 및 정책 태도Clinical Trial Published on 2021-04-072022-08-13 Journal: PLoS ONE [Category] Medicine and Health Sciences, MERS, SARS, 임상, [키워드] adjust American Americans analyses Analysis approach battery Characteristics COVID-19 COVID-19 pandemic death dependent variable dependent variables early stage Evidence Government Health health behaviors Health crisis Local National objective pandemic predictors preference preferences President public health emergency response Result reveal selected Support [DOI] 10.1371/journal.pone.0249596 PMC 바로가기 [Article Type] Clinical Trial
Prevalence of depression, anxiety and post-traumatic stress disorder in health care workers during the COVID-19 pandemic: A systematic review and meta-analysisCOVID-19 전염병 동안 의료 종사자의 우울증, 불안 및 외상 후 스트레스 장애의 유병률: 체계적인 검토 및 메타 분석Research Article Published on 2021-03-102022-08-13 Journal: PLoS ONE [Category] COVID-19, Medicine and Health Sciences, SARS, [키워드] 95% CI Anxiety Appropriate benefit Chinese CINAHL CNKI conducted covariates COVID-19 COVID-19 pandemic CQVIP database Depression disorder effective English estimate global health Google Scholar Health care Health care worker health care workers highest Inclusion Intervention Mental disorder Mental Disorders Meta-analysis meta-regression analysis Mild moderate objective outcome measure Post-traumatic stress disorder Prevalence provided Psychological Psychological stress PsycINFO PTSD Research Result SinoMed Stress Support systematic review WanfangMed Web of Science [DOI] 10.1371/journal.pone.0246454 PMC 바로가기 [Article Type] Research Article
The role of children in the spread of COVID-19: Using household data from Bnei Brak, Israel, to estimate the relative susceptibility and infectivity of childrenCOVID-19 확산에서 어린이의 역할: 이스라엘 Bnei Brak의 가구 데이터를 사용하여 어린이의 상대적 감수성과 감염력 추정Research Article Published on 2021-02-112022-08-13 Journal: PLoS Computational Biology [Category] Medicine and Health Sciences, MERS, 치료기술, [키워드] 95% CI addition adjust Adults affected age approach average chance children city collected Combination confirmed COVID-19 case Contact COVID-19 detection rate discrete stochastic model Epidemiology estimate example explain groups household household size Households increase index cases individual individuals infect Infection infectivity parameter Inspection joint less likelihood mathematical mathematical model multiple imputation procedure observation offset parameter PCR PCR positive PCR testing performed positive question reduced relative susceptibility Schools serological data serological test Serological tests Spread spread of COVID-19 subset susceptibility susceptible tested Transmission transmission parameters under-detection [DOI] 10.1371/journal.pcbi.1008559 PMC 바로가기 [Article Type] Research Article
Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusionSARS-CoV-2 스파이크의 푸린 절단은 감염 및 세포-세포 융합을 촉진하지만 필수적이지는 않습니다Research Article Published on 2021-01-252022-08-13 Journal: PLoS Pathogens [Category] COVID-19, Medicine and Health Sciences, [키워드] ACE2 ACE2 receptor activate activated acute respiratory syndrome coronavirus Amino acid Antiviral antiviral therapies attachment binding Cell cell-cell fusion cells cellular protease cellular proteases cleavage cleaved cocktail coronavirus COVID-19 pandemic CRISPR CRISPR-Cas9 Donor drug focus furin furin cleavage furin inhibitor furin inhibitors furin knockout cell furin knockout cells furin protease fusion fusion peptide host cell host cell membrane host cell receptor infect infected cell Infection inhibitor inhibitors motif multibasic site multinucleated cells mutant Mutation peptide pre-activation Prevent promote protease protease TMPRSS2 Protein reduce reduces required Research respiratory responsible reveal S protein S-mediated cell-cell fusion SARS-CoV-2 SARS-CoV-2 antiviral therapy SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 S SARS-CoV-2 S protein SARS-CoV-2 virus severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 spike Spread syncytia formation target cell the S protein the SARS-CoV-2 thought TMPRSS2 TMPRSS2 protease treat triggered triggering unique Viral viral infection Viral protein viral spread virus virus entry virus entry process virus-host membrane fusion [DOI] 10.1371/journal.ppat.1009246 PMC 바로가기 [Article Type] Research Article
Hydroxychloroquine-mediated inhibition of SARS-CoV-2 entry is attenuated by TMPRSS2SARS-CoV-2 진입의 Hydroxychloroquine 매개 억제는 TMPRSS2에 의해 약화됩니다Research Article Published on 2021-01-192022-08-13 Journal: PLoS Pathogens [Category] COVID-19, Medicine and Health Sciences, [키워드] ablated activate activated activating antiviral activities antiviral activity Autoimmune disorders block cathepsin L Cathepsins cause Cell cell entry cell surface cell-culture studies cell-culture systems Chloroquine cleave clinically Combination combinations coronavirus COVID-19 COVID-19 patient dependent on Efficacy endocytosis Endosomal acidification endosomal protease explain functional furin furin cleavage site furin-cleavage site global public health human clinical trial human clinical trials Hydroxychloroquine identify in vivo Infection inhibit inhibit SARS-CoV-2 interfere introduced lack malaria membrane fusion observé pathogenic coronavirus pathway plasma plasma membrane Prevent protease TMPRSS2 Protein Proteins proteolytic activity Receptor binding reversed S protein S proteins SARS Coronavirus SARS-CoV-1 SARS-CoV-1 and -2 SARS-CoV-2 SARS-CoV-2 entry SARS-COV-2 infection SARS-CoV-2 S protein SARS-CoV-2 spike shown target cell target cells tested the cell the SARS-CoV-2 these compounds TMPRSS2 TMPRSS2 expression TMPRSS2 inhibitor TMPRSS2 pathway treat treated treatment for COVID-19 utility Viral viral entry viral infection [DOI] 10.1371/journal.ppat.1009212 PMC 바로가기 [Article Type] Research Article