Abstract
The COVID-19 pandemic has resulted in the development, validation, and rapid adoption of multiple novel diagnostic approaches. Hundreds of SARS-CoV-2 serologic assays have been developed and deployed to contain the spread of the virus, and to supply timely and important health information. Most of these serologic assays were based on a conventional enzyme-linked immunosorbent assay or the lateral flow assay format. The immunoassays that were developed were based on alternative technologies and are highlighted in this article with a brief discussion of the assay principle and the pros and cons for each assay. Measurement of neutralizing antibodies is also discussed.
Keywords: ELISA; Electrochemical detection; Immunoassay; Luminescence; Neutralization assay; SARS-CoV-2; Serology.
【저자키워드】 SARS-CoV-2, serology, ELISA, immunoassay, Electrochemical detection, Neutralization assay, Luminescence, 【초록키워드】 neutralizing antibody, Neutralizing antibodies, serology, COVID-19 pandemic, diagnostic, virus, ELISA, Spread, lateral flow, immunoassays, immunoassay, enzyme-linked immunosorbent assay, Neutralization assay, health information, serologic assays, Luminescence, approaches, pros, MOST, measurement, serologic assay, enzyme-linked immunosorbent, 【제목키워드】 coronavirus 2, respiratory,