Abstract
Adequate immune response to vaccination remains a challenge in patients after solid organ transplantation. We report a case of a 61-year-old male patient who received a left ventricular assist device as a bridge to transplant therapy. Three months before transplantation, he suffered mild SARS-CoV-2 infection and was successfully discharged thereafter. Eight days before his successful heart transplantation, he received mRNA BNT 162b2 vaccination. Immediately after transplantation, we detected sufficient rise of nucleocapsid and spike antibodies despite immune suppression therapy. We suspect potential booster effects of the previous SARS-CoV-2 infection giving rise to adequate immune response following single vaccination.
Keywords: COVID-19; Immune response; Immune suppression; Orthotopic heart transplantation; SARS-CoV-2; Vaccination.
【저자키워드】 COVID-19, SARS-CoV-2, immune response, vaccination., Immune suppression, Orthotopic heart transplantation, 【초록키워드】 immune response, vaccination, therapy, antibody, SARS-COV-2 infection, solid organ transplantation, nucleocapsid, mRNA, male, Patient, Heart transplantation, booster, Immune suppression, organ transplantation, solid organ, transplantation, ventricular assist device, mild SARS-CoV-2 infection, bridge, single vaccination, Effect, Assist device, suffered, Adequate, discharged, assist, BNT, Orthotopic, ventricular, 【제목키워드】 vaccination, single dose, Adequate,