Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins were measured in longitudinal plasma samples collected from 13 participants who received two doses of mRNA-1273 vaccine. Eleven of 13 participants showed detectable levels of SARS-CoV-2 protein as early as day 1 after first vaccine injection. Clearance of detectable SARS-CoV-2 protein correlated with production of immunoglobulin G (IgG) and immunoglobulin A (IgA).
Keywords: COVID-19; SARS-CoV-2 antigens; immune responses; mRNA vaccine; spike.
All Keywords
【저자키워드】 COVID-19, spike, mRNA vaccine, immune responses, SARS-CoV-2 antigens, 【초록키워드】 severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, IgG, coronavirus, mRNA vaccine, mRNA-1273, severe acute respiratory syndrome Coronavirus, immune, Protein, Immunoglobulin G, Immunoglobulin, IgA, mRNA, immune responses, respiratory, immunoglobulin A, SARS-CoV-2 antigens, dose, mRNA-1273 vaccine, acute respiratory syndrome, acute respiratory syndrome coronavirus, participant, SARS-CoV-2 protein, clearance, plasma sample, collected, detectable, correlated, were measured, vaccine injection, 【제목키워드】 SARS-CoV-2, coronavirus 2, recipient,
【저자키워드】 COVID-19, spike, mRNA vaccine, immune responses, SARS-CoV-2 antigens, 【초록키워드】 severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, IgG, coronavirus, mRNA vaccine, mRNA-1273, severe acute respiratory syndrome Coronavirus, immune, Protein, Immunoglobulin G, Immunoglobulin, IgA, mRNA, immune responses, respiratory, immunoglobulin A, SARS-CoV-2 antigens, dose, mRNA-1273 vaccine, acute respiratory syndrome, acute respiratory syndrome coronavirus, participant, SARS-CoV-2 protein, clearance, plasma sample, collected, detectable, correlated, were measured, vaccine injection, 【제목키워드】 SARS-CoV-2, coronavirus 2, recipient,
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중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 단백질은 mRNA-1273 백신을 2회 투여받은 13명의 참가자로부터 수집한 세로 혈장 샘플에서 측정되었습니다. 13명의 참가자 중 11명은 첫 번째 백신 주사 후 빠르면 1일째에 SARS-CoV-2 단백질의 검출 가능한 수준을 보였습니다. 검출 가능한 SARS-CoV-2 단백질의 제거는 면역글로불린 G(IgG) 및 면역글로불린 A(IgA) 생성과 관련이 있습니다.
{{ 키워드: }} 코로나19; SARS-CoV-2 항원; 면역 반응; mRNA 백신; 스파이크.