We determined hepatitis B virus (HBV) suppression rates among 18 lamivudine (3TC)-experienced HBV-HIV coinfected adolescents after treatment with tenofovir disoproxil fumurate (TDF). At TDF initiation, their median age was 17.6 years, and duration of 3TC-exposure was 7.3 years. Eleven patients (61%) achieved HBV DNA <60 IU/mL after 48 weeks on TDF and 3TC which was similar to adult studies, although HBsAg loss or HBeAb seroconversion did not occur.
All Keywords
【저자키워드】 HIV, adolescents, Asia, hepatitis B, tenofovir,
【저자키워드】 HIV, adolescents, Asia, hepatitis B, tenofovir,