Abstract
The infectious disease Coronavirus 2019 (COVID-19) continues to cause a global pandemic and, thus, the need for effective therapeutics remains urgent. Global research targeting COVID-19 treatments has produced numerous therapy-related data and established data repositories. However, these data are disseminated throughout the literature and web resources, which could lead to a reduction in the levels of their use. In this review, we introduce resource repositories for the development of COVID-19 therapeutics, from the genome and proteome to antiviral drugs, vaccines, and monoclonal antibodies. We briefly describe the data and usage, and how they advance research for therapies. Finally, we discuss the opportunities and challenges to preventing the pandemic from developing further.
Keywords: Bioinformatics; Drug design; Monoclonal antibodies; SARS-CoV-2; Sequence and structure; Vaccines.
【저자키워드】 SARS-CoV-2, Vaccines, drug design, bioinformatics, monoclonal antibodies, Sequence and structure, 【초록키워드】 COVID-19, coronavirus, pandemic, Vaccines, drug design, Genome, bioinformatics, antiviral drugs, drug, Infectious disease, monoclonal antibodies, COVID-19 therapeutics, COVID-19 treatments, global pandemic, COVID-19 treatment, Research, proteome, resource, Therapies, lead, Repository, Usage, These data, sequence, resources, effective, produced, reduction in, 【제목키워드】 COVID-19, Treatment, Drug discovery, resource, facilitate, Web,