1-O-Acetyl-2,3,5-tri-O-benzyl-4-thio-L-arabinofuranoside (6) was transformed in two steps into the 1-(4-thio-L-arabinofuranosyl)-5-halopyrimidine nucleosides 10, 11 and 12, obtained as anomeric mixtures which were separable in the case of 10 and 11. No in vitro antiviral activity against HIV-1 and HIV-2. TK+ and TK- VZV and CMV has been found for 10, 11 and 12.
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