Abstract
The aim of this study was to estimate the seroprevalence of immunoglobulin M (IgM) and G (IgG) antibodies against SARS-CoV-2 in asymptomatic people in Wuhan. This was a cross-sectional study, which enrolled 18,712 asymptomatic participants from 154 work units in Wuhan. Pearson Chi-square test, t -test, and Mann-Whitney test were used to compare the standardized seroprevalence of IgG and IgM for age and gender between different groups. The results indicated the standardized seroprevalence of IgG and IgM showed a downward trend and was significantly higher among females than males. Besides, different geographic areas and workplaces had different seroprevalence of IgG among asymptomatic people, and the number of abnormalities in CT imaging were higher in IgG antibody-positive cases than IgG-negative cases. We hope these findings can provide references for herd immunity investigation and provide basis for vaccine development.
Keywords: COVID-19; Computed tomography; IgG; IgM; SARS-CoV-2; Serological testing; Seroprevalence.
【저자키워드】 COVID-19, SARS-CoV-2, IgG, IgM, Computed tomography, Serological testing, seroprevalence., 【초록키워드】 Vaccine development, Immunity, antibody, cross-sectional, Seroprevalence, Computed tomography, cross-sectional study, IgG antibody, Asymptomatic, Immunoglobulin, Serological testing, herd immunity, Wuhan, female, immunoglobulin M, IgG and IgM, chi-square test, participant, Abnormalities, Mann-Whitney test, abnormality, t -test, Pearson chi-square test, males, enrolled, indicated, were used, significantly higher, groups, age and gender, 【제목키워드】 China, IgM and IgG, Seafood, South,