[저자] Mark E Schnute, David J Anderson, Roger J Brideau, Fred L Ciske, Sarah A Collier, Michele M Cudahy, MariJean Eggen, Michael J Genin, Todd A Hopkins, Thomas M Judge, Euibong J Kim, Mary L Knechtel, Sajiv K Nair, James A Nieman, Nancee L Oien, Allen Scott, Steven P Tanis, Valerie A Vaillancourt, Michael W Wathen, Janet L Wieber
[Category] 두창,
[Article Type] Comparative Study
[Source] pubmed
A novel series of 2-aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides have been identified as potent antivirals against human herpesviruses. These compounds demonstrate broad-spectrum inhibition of the herpesvirus polymerases HCMV, HSV-1, EBV, and VZV with high specificity compared to human DNA polymerases.
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