Abstract
The COVID-19 pandemic remains a significant problem involving health systems worldwide. Several diagnostic methods are reported for detecting the coronavirus in clinical, research, and public health laboratories. rRT-PCR is considered the gold standard; however, as it required skilled personnel and special equipment, rapid antigen tests have been developed and used as first-line screening. The serologic testing of antibodies can also be used to enhance the detection sensitivity and accuracy, which are used to assess the overall infection rate. This review summarizes the molecular techniques and serologic assays widely used in China and discusses the advantages and disadvantages of these techniques.
Keywords: Molecular diagnosis; Real-time PCR; SARS-CoV-2; Serologic assays.
【저자키워드】 SARS-CoV-2, Molecular diagnosis, Real-time PCR, Serologic assays., 【초록키워드】 public health, coronavirus, antibody, equipment, COVID-19 pandemic, health systems, China, rRT-PCR, Rapid antigen tests, Molecular diagnosis, rapid antigen test, Accuracy, Real-time PCR, serologic, Research, gold, infection rate, health system, molecular, serologic assays, serologic testing, Diagnostic method, Detection sensitivity, Disadvantages, disadvantage, gold standard, serologic assay, ENhance, reported, assays, required, 【제목키워드】 China,