Abstract
Coronavirus disease-19 (COVID-19) emerged late December 2019 in the city of Wuhan, China and has since spread rapidly all over the world causing a global pandemic. While the respiratory system is the primary target of disease manifestation, COVID-19 has been shown to also affect several other organs, making it a rather complex, multi-system disease. As such, cardiovascular involvement has been a topic of discussion since the beginning of the COVID-19 pandemic, primarily due to early reports of excessive myocardial injury in these patients. Treating physicians are faced with multiple challenges in the management and early triage of patients with COVID-19, as disease severity is highly variable ranging from an asymptomatic infection to critical cases rapidly deteriorating to intensive care treatment or even fatality. Laboratory biomarkers provide important prognostic information which can guide decision making in the emergency department, especially in patients with atypical presentations. Several cardiac biomarkers, most notably high-sensitive cardiac troponin (hs-cTn) and N-terminal pro-B-type natriuretic peptide (NT-proBNP), have emerged as valuable predictors of prognosis in patients with COVID-19. The purpose of this review was to offer a concise summary on prognostic cardiac biomarkers in COVID-19 and discuss whether routine measurements of these biomarkers are warranted upon hospital admission.
Keywords: BNP; COVID-19; cardiac biomarkers; myocardial injury; troponin.
【저자키워드】 COVID-19, troponin, Cardiac biomarkers, myocardial injury, BNP, 【초록키워드】 coronavirus disease, coronavirus, Biomarker, Biomarkers, Prognosis, Decision making, COVID-19 pandemic, disease severity, peptide, troponin, emergency department, cardiac troponin, global pandemic, Spread, myocardial injury, management, Wuhan, Patient, asymptomatic infection, Hospital admission, Respiratory system, laboratory biomarkers, predictor, prognostic, respiratory, information, NT-proBNP, disease, patients, fatality, Atypical, critical cases, Topic, Critical case, city, complex, intensive care treatment, other organs, disease manifestation, physician, N-terminal pro-B-type natriuretic peptide, while, offer, N-terminal, Affect, Myocardial, treating, Wuhan, China, shown, patients with COVID-19, pro-B-type natriuretic peptide, 【제목키워드】 cardiovascular,