During the period July 1986 through December 1991, 67 children were treated for non-B-cell acute lymphoblastic leukemia at The Juliane Marie Centre, GGK, The University Hospital Rigshospitalet, Copenhagen. Twenty-five children were susceptible to varicella zoster (VZ) virus at diagnosis. For these patients the cumulated risk of VZ exposure was 90% after 32 months. Five patients developed varicella (two of whom had pneumonitis) during the period of antileukemic treatment. Two of these had received prophylactic treatment with acyclovir. The 2 year cumulated risk of having chickenpox or herpes zoster in children with previous VZ infection was 24% and 34%, respectively. VZ vaccination ought to be considered for this group of children in order to diminish transmission and morbidity.
Varicella zoster infections in children with acute lymphoblastic leukemia
급성 림프모구 백혈병 아동에서의 수두 대상포진 감염
[Category] 대상포진, 두창, 수두,
[Source] pubmed
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