Hepatitis B morbidity in the Trebisov district (eastern Slovakia) exceeded several times the average morbidity in Slovakia in the first half of the eighties. High morbidity of children in the age groups 0-4 and 5-9, frequent extraparenteral transmission in families with sick members or with HBsAg carries (34.9%), led to the introduction of the regular vaccination of all children in their first year of life. Already during the first years of this vaccination, an important decrease of morbidity in vaccinated age groups was observed.
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