Abstract
Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that emerged late in 2019 causing COVID-19 (coronavirus disease-2019) may adversely affect the cardiovascular system. Publications from Asia, Europe, and North America have identified cardiac troponin as an important prognostic indicator for patients hospitalized with COVID-19. We recognized from publications within the first 6 months of the pandemic that there has been much uncertainty on the reporting, interpretation, and pathophysiology of an increased cardiac troponin concentration in this setting.
Content: The purpose of this mini-review is: a) to review the pathophysiology of SARS-CoV-2 and the cardiovascular system, b) to overview the strengths and weaknesses of selected studies evaluating cardiac troponin in patients with COVID-19, and c) to recommend testing strategies in the acute period, in the convalescence period and in long-term care for patients who have become ill with COVID-19.
Summary: This review provides important educational information and identifies gaps in understanding the role of cardiac troponin and COVID-19. Future, properly designed studies will hopefully provide the much-needed evidence on the path forward in testing cardiac troponin in patients with COVID-19.
Keywords: COVID-19; acute care; cardiac troponin; risk stratification.
【저자키워드】 COVID-19, cardiac troponin, risk stratification, acute care, 【초록키워드】 coronavirus disease, SARS-CoV-2, coronavirus, Europe, pandemic, troponin, cardiovascular system, severe acute respiratory syndrome Coronavirus, cardiac troponin, Asia, risk stratification, pathophysiology, Patient, Interpretation, Long-term care, Reporting, respiratory, information, Care, Evidence, Concentration, acute respiratory syndrome, acute respiratory syndrome coronavirus, acute respiratory syndrome coronavirus 2, North America, path, prognostic indicator, Future, Affect, selected, identify, provide, patients hospitalized, patients with COVID-19, with COVID-19, 【제목키워드】 Strategy, Testing, cardiac, Result,