Abstract
The last few years have increasingly emphasized the need to develop new active antiviral products obtained from artificial synthesis processes using nanomaterials, but also derived from natural matrices. At the same time, advanced computational approaches have found themselves fundamental in the repurposing of active therapeutics or for reducing the very long developing phases of new drugs discovery, which represents a real limitation, especially in the case of pandemics. The first part of the review is focused on the most innovative nanomaterials promising both in the field of therapeutic agents, as well as measures to control virus spread (i.e., innovative antiviral textiles). The second part of the review aims to show how computer-aided technologies can allow us to identify, in a rapid and therefore constantly updated way, plant-derived molecules (i.e., those included in terpenoids) potentially able to efficiently interact with SARS-CoV-2 cell penetration pathways.
Keywords: SARS-CoV-2; antiviral activity; drug delivery systems; molecular docking; nanodecoys; nanosystems; terpenoids; virus spread control measures.
【저자키워드】 SARS-CoV-2, molecular docking, antiviral activity, terpenoids, drug delivery systems, nanodecoys, nanosystems, virus spread control measures., 【초록키워드】 Antiviral, molecular docking, drug, antiviral activity, Measures, Pandemics, therapeutic agents, molecular, nanomaterials, Pathways, virus spread, measure, penetration, identify, develop, reducing, increasingly, computational approach, SARS-CoV-2 cell, 【제목키워드】 technology, drug, Nanomaterial, Potential,