Abstract
The coronavirus disease 2019 (COVID-19) pandemic has underscored the lack of approved drugs against acute viral diseases. Plants are considered inexhaustible sources of drugs for several diseases and clinical conditions, but plant-derived compounds have seen little success in the field of antivirals. Here, we present the case for the use of compounds from vascular plants, including alkaloids, flavonoids, polyphenols, and tannins, as antivirals, particularly for the treatment of COVID-19. We review current evidence for the use of these phytochemicals against SARS-CoV-2 infection and present their potential targets in the SARS-CoV-2 replication cycle.
Keywords: COVID-19; SARS-CoV-2; alkaloids; antivirals; coronaviruses; flavonoids; natural products; phytochemicals.
【저자키워드】 COVID-19, SARS-CoV-2, Coronaviruses, antivirals, natural products, flavonoids, alkaloids, phytochemicals., 【초록키워드】 Treatment, coronavirus disease, Coronavirus disease 2019, pandemic, SARS-COV-2 infection, flavonoids, drug, approved drugs, Replication, plants, target, plant, disease, Evidence, approved drug, Vascular, tannins, treatment of COVID-19, Compound, clinical conditions, acute viral diseases, lack, the SARS-CoV-2, 【제목키워드】 Treatment, phytochemical,