Abstract
Although the use of corticosteroids is not recommended in the World Health Organization statement for the treatment of coronavirus disease 2019 (COVID-19), steroid therapy may be indicated for critical cases in specific situations. Here, we report the successful treatment of 11 cases of severe COVID-19 pneumonia with favipiravir and methylprednisolone. All cases were severe and patients required oxygen administration or had a blood oxygen saturation ≤93% on room air. All were treated with favipiravir and methylprednisolone, and 10 of 11 patients responded well and required no further oxygen supplementation or ventilator management. This study shows the importance of the early-stage use of a combination of favipiravir and methylprednisolone in severe cases to achieve a favorable clinical outcome.
Keywords: Favipiravir; Methylprednisolone; Novel coronavirus disease 2019; Severe illness.
【저자키워드】 Methylprednisolone, Favipiravir, Novel coronavirus disease 2019, severe illness, 【초록키워드】 COVID-19, Methylprednisolone, Treatment, coronavirus disease, Coronavirus disease 2019, Severe COVID-19 pneumonia, Corticosteroids, COVID-19 pneumonia, therapy, Favipiravir, oxygen, novel coronavirus disease, Novel coronavirus, Clinical outcome, management, Patient, severe cases, novel, Combination, critical cases, steroid, Health Organization, room air, steroid therapy, World Health Organization, Oxygen administration, Blood oxygen saturation, Critical case, ventilator, Severe case, oxygen supplementation, indicated, required, treated, use of corticosteroid, 【제목키워드】 Methylprednisolone, severe COVID-19, Favipiravir, combination treatment,