Abstract
The coronavirus disease 2019 (COVID-19) pandemic, which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has killed more than one million people as of October 1, 2020. Consequently, a search is on for a treatment that can bring the pandemic to an end. However, treatments (vaccine, antiviral, plasma) that are directed at specific viral proteins (RNA polymerase, spike proteins) may not work well against all strains of the virus. Therefore, it is hypothesized that a therapy based on multiple treatments is needed for COVID-19 patients and to bring the pandemic to an end. Here, it is proposed that a combination of cool air therapy (CAT) and purified air technology (PAT) in an oxygen species cool air respirator (OSCAR) could be used to reduce viral (SARS-CoV-2) load and severity of illness in COVID-19 patients through the individual dose-response relationship. In addition, the proposed therapy (CAT + PAT in OSCAR), which works by a more general physical and chemical mechanism, should work well with other treatments (vaccine, antiviral, plasma) that target specific viral proteins (RNA polymerase, spike proteins) to provide a safe and effective multiple therapy approach for ending the COVID-19 pandemic caused by SARS-CoV-2.
Keywords: COVID-19; Cool air therapy; Coronavirus; Dose–response; Oxygen species cool air respirator; Pandemic; Purified air technology; SARS-CoV-2.
【저자키워드】 COVID-19, SARS-CoV-2, coronavirus, pandemic, Cool air therapy, Dose–response, Oxygen species cool air respirator, Purified air technology, 【초록키워드】 Treatment, coronavirus disease, SARS-CoV-2, Coronavirus disease 2019, Vaccine, coronavirus, therapy, Antiviral, COVID-19 pandemic, severity, oxygen, Viral proteins, severe acute respiratory syndrome Coronavirus, virus, Viral, plasma, RNA polymerase, respiratory, mechanism, COVID-19 patients, Combination, Spike proteins, strain, COVID-19 patient, Safe, severity of illness, dose-response relationship, Respirator, acute respiratory syndrome, Viral protein, acute respiratory syndrome coronavirus, acute respiratory syndrome coronavirus 2, other treatments, approach, physical, effective, OSCAR, caused, addition, reduce, purified, other treatment, 【제목키워드】 Treatment, therapy, Hypothesis, COVID-19 patient,