Abstract
Interferons are our first line of defense against invading viruses. However, viruses encode effector proteins that can modulate human interferon responses. In this forum article, we highlight important discoveries and discuss outstanding questions that will enable us to better understand the nuances of this evolutionary battle between interferons and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Keywords: SARS-CoV-2; innate immunity; interferon; interferon-stimulated genes; virus–host interaction.
All Keywords
【저자키워드】 SARS-CoV-2, Innate immunity, interferon, interferon-stimulated genes, virus–host interaction., 【초록키워드】 viruses, coronavirus, Innate immunity, interferons, interferon, severe acute respiratory syndrome Coronavirus, virus, interferon-stimulated genes, Interaction, acute respiratory syndrome, acute respiratory syndrome coronavirus, acute respiratory syndrome coronavirus 2, Defense, effector proteins, nuances, responses, highlight, question, modulate, effector protein, nuance,
【저자키워드】 SARS-CoV-2, Innate immunity, interferon, interferon-stimulated genes, virus–host interaction., 【초록키워드】 viruses, coronavirus, Innate immunity, interferons, interferon, severe acute respiratory syndrome Coronavirus, virus, interferon-stimulated genes, Interaction, acute respiratory syndrome, acute respiratory syndrome coronavirus, acute respiratory syndrome coronavirus 2, Defense, effector proteins, nuances, responses, highlight, question, modulate, effector protein, nuance,
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인터페론은 침입하는 바이러스에 대한 우리의 첫 번째 방어선입니다. 그러나 바이러스는 인간 인터페론 반응을 조절할 수 있는 효과기 단백질을 암호화합니다. 이 포럼 기사에서는 중요한 발견을 강조하고 인터페론과 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 간의 진화적 전투의 뉘앙스를 더 잘 이해할 수 있게 해주는 뛰어난 질문에 대해 논의합니다.
{{ 키워드: }} SARS-CoV-2; 선천성 면역; 인터페론; 인터페론 자극 유전자; 바이러스-숙주 상호작용.