Abstract
Coronavirus disease 2019 (COVID-19) and vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are associated with cardiovascular complications. Here, we report a case of right-sided heart failure caused by constrictive pericarditis that developed after the administration of messenger ribonucleic acid (mRNA) vaccine against SARS-CoV-2. A 70-year-old woman presented with body weight gain, peripheral edema, and dyspnea on effort, which developed over a period of 1 week after the second dose of vaccine. The jugular venous pressure was high with a prominent y descent (Friedreich’s sign) and paradoxical increase on inspiration (Kussmaul’s sign). The results of IgM and IgG testing specific to SARS-CoV-2 spike and nucleocapsid proteins indicated the presence of mRNA vaccine-induced antibody and were not suggestive of COVID-19 infection. Echocardiography showed pericardial thickening and septal bounce of the interventricular septum. Computed tomography (CT) also showed pericardial thickening compared with the results of the previous CT scan performed 4 months earlier. A diagnosis of right-sided heart failure due to constrictive pericarditis was confirmed on the basis of pressure analysis during cardiac catheterization.
Keywords: COVID-19; Constrictive pericarditis; SARS-CoV-2; Vaccination.
【저자키워드】 COVID-19, SARS-CoV-2, vaccination, Constrictive pericarditis, 【초록키워드】 coronavirus disease, Coronavirus disease 2019, Vaccine, coronavirus, vaccination, antibody, mRNA vaccine, body weight, Diagnosis, tomography, severe acute respiratory syndrome Coronavirus, nucleocapsid protein, echocardiography, heart failure, Computed tomography, COVID-19 infection, mRNA, CT scan, Dyspnea, edema, SARS-CoV-2 spike, administration, Constrictive pericarditis, Analysis, cardiovascular complications, IgM and IgG, Ribonucleic acid, weight gain, cardiac catheterization, acute respiratory syndrome, acute respiratory syndrome coronavirus, acute respiratory syndrome coronavirus 2, second dose, second dose of vaccine, Nucleocapsid proteins, effort, inspiration, venous, Interventricular septum, jugular venous pressure, peripheral edema, Venous pressure, performed, caused, indicated, catheterization, paradoxical, septal, 【제목키워드】 Case report, Constrictive pericarditis,