Abstract
Several studies have reported that certain psychoactive drugs could have a protective effect against SARS-CoV-2. Herein, we propose that antihistamines (anti-H1) and cationic amphiphilic drugs (CAD), specifically, have the capacity to disrupt virus entry and replication. In addition, several of these molecules have limited side effects and as such could be promising prophylactic candidates against SARS-CoV-2 infection.
All Keywords
【초록키워드】 SARS-CoV-2, SARS-COV-2 infection, drug, Prophylactic, Replication, virus entry, Side effects, protective effect, CAD, Side effect, Antihistamines, candidate, reported, addition, disrupt, cationic, 【제목키워드】 drugs, Antihistamine, cationic,
【초록키워드】 SARS-CoV-2, SARS-COV-2 infection, drug, Prophylactic, Replication, virus entry, Side effects, protective effect, CAD, Side effect, Antihistamines, candidate, reported, addition, disrupt, cationic, 【제목키워드】 drugs, Antihistamine, cationic,
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여러 연구에서 특정 향정신성 약물이 SARS-CoV-2에 대한 보호 효과가 있을 수 있다고 보고했습니다. 여기에서 우리는 항히스타민제(anti-H1)와 양이온성 양친매성 약물(CAD)이 특히 바이러스 진입과 복제를 방해하는 능력이 있다고 제안합니다. 또한 이러한 분자 중 몇 가지는 부작용이 제한적이므로 SARS-CoV-2 감염에 대한 유망한 예방 후보가 될 수 있습니다.