Abstract
SARS-CoV-2 is the novel coronavirus behind the COVID-19 pandemic. Since its emergence, the global scientific community has mobilized to study this virus, and an overwhelming effort to identify COVID-19 treatments is currently ongoing for a variety of therapeutics and prophylactics. To better understand these efforts, we compiled a list of all COVID-19 vaccines undergoing preclinical and clinical testing using the WHO and ClinicalTrials.gov database, with details surrounding trial design and location. The most advanced vaccines are discussed in more detail, with a focus on their technology, advantages and disadvantages, as well as any available recent clinical findings. We also cover some of the primary challenges, safety concerns and public responses to COVID-19 vaccine trials, and consider what this can mean for the future. By compiling this information, we aim to facilitate a more thorough understanding of the extensive COVID-19 clinical testing vaccine landscape as it unfolds, and better highlight some of the complexities and challenges being faced by the joint effort of the scientific community in finding a prophylactic against COVID-19.
Keywords: COVID-19; COVID-19 drug treatment; SARS virus; antiviral agents; coronavirus; coronavirus infections; immunosuppressive agents; pandemics; severe acute respiratory syndrome coronavirus 2; vaccines.
【저자키워드】 COVID-19, severe acute respiratory syndrome coronavirus 2, coronavirus, Vaccines, COVID-19 drug treatment, SARS virus, Coronavirus infections, Antiviral agents, Pandemics, Immunosuppressive agents, 【초록키워드】 SARS-CoV-2, Vaccine, COVID-19 vaccine, Trial, Antiviral, Vaccines, Therapeutics, COVID-19 drug treatment, COVID-19 pandemic, Prophylactic, severe acute respiratory syndrome Coronavirus, virus, database, COVID-19 treatments, Novel coronavirus, SARS virus, COVID-19 treatment, Coronavirus infections, Clinical findings, response, Antiviral agents, Pandemics, location, Scientific community, drug treatment, information, Immunosuppressive agents, Disadvantages, immunosuppressive, acute respiratory syndrome, acute respiratory syndrome coronavirus, acute respiratory syndrome coronavirus 2, COVID-19 vaccine trials, effort, list, clinical testing, global scientific community, highlight, joint, identify, facilitate, variety, the WHO, 【제목키워드】 COVID-19 vaccine,