TOC Summary: Death rates from all causes were lower than in some recent influenza seasons, particularly among older persons. In temperate countries, death rates increase in winter, but influenza epidemics often cause greater increases. The death rate time series that occurs without epidemic influenza can be called a seasonal baseline. Differentiating observed death rates from the seasonally oscillating baseline provides estimated influenza-associated death rates. During 2003–2009 in New South Wales, Australia, we used a Serfling approach with robust regression to estimate age-specific weekly baseline all-cause death rates. Total differences between weekly observed and baseline rates during May–September provided annual estimates of influenza-associated death rates. In 2009, which included our first wave of pandemic (H1N1) 2009, the all-age death rate was 6.0 (95% confidence interval 3.1–8.9) per 100,000 persons lower than baseline. In persons > 80 years of age, it was 131.6 (95% confidence interval 126.2–137.1) per 100,000 lower. This estimate is consistent with a pandemic virus causing mild illness in most persons infected and sparing older persons.
【저자키워드】 viruses, Mortality, Influenza, Human, Australia, disease outbreaks, Research, Pandemic (H1N1) 2009,