An oseltamivir-resistant influenza A pandemic (H1N1) 2009 virus evolved and emerged from zero to 52% of detectable virus within 48 hours of a patient’s exposure to oseltamivir. Phylogenetic analysis and data gathered by pyrosequencing and cloning directly on clinical samples suggest that the mutant emerged de novo.
All Keywords
【저자키워드】 viruses, oseltamivir, Influenza, antimicrobial resistance, drug resistance, Singapore, dispatch, Pandemic (H1N1) 2009,
【저자키워드】 viruses, oseltamivir, Influenza, antimicrobial resistance, drug resistance, Singapore, dispatch, Pandemic (H1N1) 2009,