One year after the emergence of the 2009 influenza (H1N1) pandemic, most cases have been relatively mild; however, the possibility of enhanced viral growth ability by reassortment with seasonal viruses cannot be overlooked. Here, we show that reassortant viruses containing a seasonal H1 HA and swine-origin NA and M genes have enhanced virus growth over their wild-type parental viruses. The emergence of such viruses in nature could, therefore, represent a threat.
All Keywords
【저자키워드】 pandemic, Influenza virus, seasonal, Reassortment, swine-origin,
【저자키워드】 pandemic, Influenza virus, seasonal, Reassortment, swine-origin,