Abstract
A recent study highlights the presence of a unique memory-like natural killer (NK) cell subset, which accumulates with aging and appears to associate withdisease severity in COVID-19 patients. While the clinical relevance of memory in NK cells is being debated, the molecular identity of this subset in the form of a single-cell transcriptome is essential to define their origin, longevity, functions, and disease relevance.
Keywords: Memory-like NK cells, Aging, Inflammaging, HCMV, COVID-19.
All Keywords
【저자키워드】 Memory-like NK cells, Aging, Inflammaging, HCMV, COVID-19., 【초록키워드】 COVID-19, Transcriptome, aging, severity, NK cell, NK cells, memory, inflammaging, molecular, Longevity, disease, single-cell, COVID-19 patients, identity, natural killer, functions, while, HCMV, Cell, highlight, appear, unique, to define, subset, accumulate, 【제목키워드】 NK cell, Perspective,
【저자키워드】 Memory-like NK cells, Aging, Inflammaging, HCMV, COVID-19., 【초록키워드】 COVID-19, Transcriptome, aging, severity, NK cell, NK cells, memory, inflammaging, molecular, Longevity, disease, single-cell, COVID-19 patients, identity, natural killer, functions, while, HCMV, Cell, highlight, appear, unique, to define, subset, accumulate, 【제목키워드】 NK cell, Perspective,
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최근 연구에서는 노화와 함께 축적되고 COVID-19 환자의 질병 중증도와 관련이 있는 것으로 보이는 고유한 기억 유사 자연 살해(NK) 세포 하위 집합의 존재를 강조합니다. NK 세포에서 기억의 임상적 관련성이 논의되고 있는 동안, 단일 세포 전사체 형태의 이 하위 집합의 분자적 동일성은 기원, 수명, 기능 및 질병 관련성을 정의하는 데 필수적입니다.
{{ 키워드: }} 기억 유사 NK 세포, 노화, 염증, HCMV, 코로나19.