Abstract
Reverse transcription-polymerase chain reaction (RT-PCR) tests for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), are approved for qualitative use. The cycle threshold (Ct) value reflects the concentration of viral RNA in the sample, with lower Ct values indicating higher levels of RNA. Caregivers may wish to use the Ct value to determine the progression of infection, how severe the infection will be, and whether the patient can transmit the virus. Variability of Ct values and the data supporting these uses should be considered when deciding whether and how to use Ct values in clinical care.
Keywords: COVID-19; Cycle threshold value; Reverse transcription-polymerase chain reaction; SARS-CoV-2.
【저자키워드】 COVID-19, SARS-CoV-2., Reverse transcription-polymerase chain reaction, Cycle threshold value, 【초록키워드】 coronavirus disease, SARS-CoV-2, Coronavirus disease 2019, Infection, progression, severe acute respiratory syndrome Coronavirus, RT-PCR, virus, RNA, Severe acute respiratory syndrome, polymerase chain reaction, cycle threshold, Ct value, Caregivers, reverse transcription, Viral RNA, clinical care, threshold, Reverse transcription-polymerase chain reaction, Coronavirus-2, Concentration, Caregiver, Cycle threshold value, Ct values, Chain Reaction, acute respiratory syndrome, acute respiratory syndrome coronavirus, cycle, Variability, acute respiratory syndrome coronavirus-2, the patient, approved, determine, reflect, 【제목키워드】 respiratory, reaction, cycle, chain, value, Potential,