Abstract
An acute respiratory syndrome (COVID-19), caused by a novel coronavirus (SARS-CoV-2) with a high rate of morbidity and elevate mortality, has emerged as one of the most important threats to humankind in the last centuries. Rigorous determination of SARS-CoV-2 infectivity is very difficult owing to the continuous evolution of the virus, with its single nucleotide polymorphism (SNP) variants and many lineages. However, it is urgently necessary to study the virus in depth, to understand the mechanism of its pathogenicity and virulence, and to develop effective therapeutic strategies. The present contribution summarizes in a succinct way the current knowledge on the evolutionary and structural features of the virus, with the aim of clarifying its mutational pattern and its possible role in the ongoing pandemic.
Keywords: Evolution pattern; Mutation; Pandemic; SARS-CoV-2.
【저자키워드】 SARS-CoV-2, pandemic, Mutation, Evolution pattern, 【초록키워드】 COVID-19, Evolution, SARS-CoV-2, Mutation, Mortality, knowledge, threat, variant, polymorphism, virus, Novel coronavirus, Single nucleotide polymorphism, morbidity, Therapeutic strategies, SNP, respiratory, pathogenicity, virulence, single nucleotide, lineages, mechanism, nucleotide, acute respiratory syndrome, feature, effective, develop, caused, 【제목키워드】 genome variant,