Objective: To analyze the epidemiological characteristics of hepatitis E Virus antibody (anti-HEV) in people aged 1-29 years in China in 2014. Methods: Based on database of the national serologic survey of hepatitis B in people aged 1-29 years in China, in 2014, the sample size was estimated. The serum samples of the people surveyed were randomly selected to detect anti-HEV IgG by using enzyme- linked immunosorbent assay (ELISA). Statistical software SAS 9.1.3 was used to calculate the positive rate of anti-HEV and 95 % confidence interval ( CI ) in different age, gender groups, urban and rural areas and geographic areas by using the Taylor series linear method with sampling weight. The difference was determined by comparing 95 %CI . Results: A total of 14 106 serum samples were detected from people aged 1-29 years, including 6 996 males (49.60 % ), 7 013 urban residents (49.72 % ). The positive rate of anti-HEV was 8.12 % (95 %CI : 7.19-9.15) in people aged 1-29 years. There was no statistical difference between the men and women, between urban area and rural area. The positive rates of anti-HEV in western area(11.36 % , 95 %CI : 9.45-13.62) was higher than those in eastern and central areas. The positive rates of anti-HEV were 2.46 % , 2.24 % , 4.50 % , 7.58 % , 11.89 % and 17.27 % in people aged 1-, 5-, 10-, 15-, 20- and 25-29 years, respectively. As the age increased, the positive rate of anti-HEV gradually increased. In different ethnic groups, the positive rate of anti-HEV was higher in Tibetan (18.32 % , 95 %CI : 12.02-26.90), Zhuang (9.54 % , 95 %CI : 4.33-19.73) ethnic groups. Conclusion: The positive rate of anti-HEV declined slightly in China in 2014. It is still necessary to pay close attention to the HEV infection, morbidity of hepatitis E and risk factors in people aged 1-29 years.
【저자키워드】 serology, hepatitis E, Epidemiologic characteristic,