Abstract
There is limited information on the specific impact of maternal infection with the SARS-CoV-2 B.1.617.2 (delta) variant on pregnancy outcomes. We present 2 cases of intrauterine fetal demise and 1 case of severe fetal distress in the setting of maternal infection with delta-variant SARS-CoV-2. In all cases, fetal demise or distress occurred within 14 days of COVID-19 diagnosis. Evaluation revealed maternal viremia, high nasopharyngeal viral load, evidence of placental infection with delta-variant SARS-CoV-2, and hallmark features of SARS-CoV-2 placentitis. We suggest that delta-variant SARS-CoV-2 infection during pregnancy warrants vigilance for placental dysfunction and fetal compromise regardless of disease severity.
Keywords: COVID-19; SARS-CoV-2 placentitis; delta variant; placental infection; pregnancy; stillbirth.
【저자키워드】 COVID-19, delta variant, Pregnancy, SARS-CoV-2 placentitis, Placental infection, stillbirth., 【초록키워드】 SARS-CoV-2, SARS-COV-2 infection, disease severity, variant, Infection, B.1.617.2, delta variant, outcomes, Pregnancy, Stillbirth, Viremia, COVID-19 diagnosis, placental, information, placental dysfunction, Evidence, Placental infection, distress, placentitis, evidence of, during pregnancy, fetal distress, dysfunction, demise, hallmark, feature, nasopharyngeal viral load, occurred, fetal, the SARS-CoV-2, 【제목키워드】 SARS-CoV-2, Delta, B.1.617.2,