Abstract
Nationally, the 18-49 years old age group are less likely to be vaccinated compared to those 50 years and older. Data describing the risk of COVID-19 severe illness that requires hospitalization among younger healthy adults is limited. In an effort to underscore the importance of vaccination and provide data that may influence COVID-19 risk perception, COVID-19 data of a sample of hospitalized non-elderly age group who clinically may not be considered as high risk for severe COVID-19 illness are presented. Specifically, this retrospective chart review (spanning the period of March 2020 to September 2021) provides a descriptive analysis examining the characteristics, vaccination status and outcomes of adults who were hospitalized at Memorial Healthcare System with laboratory-confirmed COVID-19. The study’s data focuses on non-pregnant adults, aged 18-49 years old, without underlying conditions and with no reported history of smoking. As a sub-analysis, data on young and otherwise healthy pregnant females who were hospitalized with COVID-19, as well as data stratified by the pre-Delta and Delta variant dominant period are also presented. There was a total of 482 young and otherwise healthy non-pregnant adults who were hospitalized with COVID-19. Overall, more than 13% of our study population had severe COVID-19 disease. Further, a higher proportion of unvaccinated patients had severe COVID-19 compared to those who received at least one dose of the vaccine. All ventilator or ECMO placements, 30-day readmissions and deaths occurred among unvaccinated patients.
Keywords: Hospitalization; Infectious disease; SARS-CoV-2; Vaccination; Young adults.
【저자키워드】 SARS-CoV-2, vaccination, Hospitalization, Infectious disease, young adults, 【초록키워드】 COVID-19, Hospitalized, severe COVID-19, Infectious disease, outcome, smoking, delta variant, COVID-19 disease, Adults, Characteristics, Patient, Descriptive analysis, death, ECMO, age, underlying conditions, patients, severe COVID-19 disease, readmission, retrospective, dose, high risk, old age, history of smoking, Vaccination Status, Risk perception, Older, ventilator, Laboratory-confirmed COVID-19, study population, COVID-19 illness, effort, laboratory-confirmed, severe COVID-19 illness, dominant, System, risk of COVID-19, occurred, proportion, healthy, reported, clinically, provide, less, underlying condition, the vaccine, stratified, Memorial, pregnant female, with COVID-19, 【제목키워드】 Region, status, South, Public, System,