Abstract
Since the outbreak of coronavirus disease 2019 (COVID-19), countries all over the world have suffered severe losses. It affects not only human life and health but also the economy. In response to COVID-19, countries have made tremendous efforts to vaccine development. The newly discovered variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have brought major challenges to the effectiveness and research of vaccines. This article reviews the existing literature and summarizes the main variants of the SARS-CoV-2 and its impact on vaccines, and provides new ideas for the later development of vaccines. An excellent job in developing and applying vaccines will be an important measure for epidemic prevention and control.
Keywords: COVID-19; SARS-CoV-2; spike protein; vaccines; variants.
【저자키워드】 COVID-19, SARS-CoV-2, Vaccines, Spike protein, variants., 【초록키워드】 coronavirus disease, Coronavirus disease 2019, Vaccine, Vaccine development, coronavirus, variant, Economy, severe acute respiratory syndrome Coronavirus, variants, Spike protein, Epidemic, Health, outbreak, Research, Effectiveness, Prevention and control, acute respiratory syndrome, acute respiratory syndrome coronavirus, acute respiratory syndrome coronavirus 2, effort, Affect, country, provide, suffered, the SARS-CoV-2, 【제목키워드】 Vaccine, variants of SARS-CoV-2,