Abstract
During the global COVID-19 pandemic, data from clinical studies, systematic review, and population registry data have shown that when compared with non-pregnant women, SARS-CoV-2 infection in pregnancy is associated with a small increase in risk to the mother. Large cohort studies and registry data collected from 2020 have included the US Surveillance for Emerging Threats to Mothers and Babies Network (SET-NET), COVI-PREG, the UK and Global Pregnancy and Neonatal Outcomes in COVID-19 (PAN-COVID) study, the American Academy of Pediatrics (AAP) Section on Neonatal-Perinatal Medicine (SONPM) National Perinatal COVID-19 Registry, the Swedish Pregnancy Register, and the Canadian Surveillance of COVID-19 in Pregnancy (CANCOVID-Preg) registry. Recently published data have shown that most maternal infections with SARS-CoV-2 occur during the third trimester and result in a small increase in hospital admission, admission to the intensive care unit (ICU), mechanical ventilation, preterm birth, and increased cesarean sections in mothers infected with SARS-CoV-2. However, currently approved vaccines given in pregnancy result in an immune response to current SARS-CoV-2 variants. Transplacental transmission of SARS-CoV-2 to the fetus can occur, but the immediate and long-term effects on the newborn infant remain unclear. Therefore, women who are pregnant or planning a pregnancy should be managed according to current clinical guidelines with timely vaccination to prevent infection with SARS-CoV-2. This Editorial summarizes what is currently known about maternal SARS-CoV-2 infection and pregnancy outcomes from multinational studies.
【초록키워드】 COVID-19, SARS-CoV-2, Vaccine, immune response, vaccination, intensive care, mechanical ventilation, threat, SARS-COV-2 infection, COVID-19 pandemic, Infection, intensive care unit, systematic review, risk, outcome, ICU, cohort study, Medicine, pediatrics, Pregnancy, Preterm birth, SARS-CoV-2 variants, Perinatal, Clinical studies, fetus, transplacental transmission, network, Hospital admission, women, registry, Admission, baby, mother, pregnant, Neonatal, Section, registry data, editorial, Effect, clinical guideline, Prevent, Academy, newborn infant, shown, collected, approved, occur, increase in, Swedish, infected with SARS-CoV-2, infection with SARS-CoV-2, 【제목키워드】 SARS-CoV-2, Maternal, current,