Abstract
Due to global shortages of flocked nasopharyngeal swabs and appropriate viral transport media during the COVID-19 pandemic, alternate diagnostic specimens for SARS-CoV-2 detection are sought. The accuracy and feasibility of saliva samples collected and transported without specialized collection devices or media were evaluated. Saliva demonstrated good concordance with paired nasopharyngeal swabs for SARS-CoV-2 detection in 67/74 cases (90.5%), though barriers to saliva collection were observed in long-term care residents and outbreak settings. SARS-CoV-2 RNA was stable in human saliva at room temperature for up to 48 h after initial specimen collection, informing appropriate transport time and conditions.
Keywords: COVID-19; Nasopharyngeal; SARS-CoV-2; Saliva; Transport.
【저자키워드】 COVID-19, SARS-CoV-2, Saliva, nasopharyngeal, Transport, 【초록키워드】 Saliva, feasibility, COVID-19 pandemic, diagnostic, media, Nasopharyngeal swab, SARS-CoV-2 detection, Viral, Concordance, Accuracy, outbreak, nasopharyngeal swabs, human saliva, Long-term care, temperature, SARS-CoV-2 RNA, viral transport media, Care, room temperature, specimen collection, Transport, specimen, saliva samples, initial, collected, evaluated, demonstrated, conditions, transported, 【제목키워드】 implementation,