Clinical efficacy of nitric oxide nasal spray (NONS) for the treatment of mild COVID-19 infection

Published on
Journal: The Journal of Infection
[저자] Stephen Winchester, Sarah John, Kashif Jabbar, Isaac John
[Category] MERS, SARS,
PMC URL    Pubmed URL    [DOI] 10.1016/j.jinf.2021.05.009    
[Article Type] Comment
[Source] PMC

Abstract
Baek et al. 1 investigated the duration of COVID-19 virus shedding in infected patients and demonstrated that even in patients demonstrating prolonged viral clearance, the virus was no longer viable after 15 days post onset of symptoms. Our study aimed to measure whether nitric oxide nasal spray (NONS) further accelerates this reduction in SARS-CoV-2 RNA load versus a control arm with saline spray. Our study recruited 80 participants who were divided into a NONS treatment arm or a placebo arm to test the efficacy of NONS as a treatment for mild COVID-19 infection.
Keywords: Antimicrobial; Antiviral; COVID-19; Coronavirus; Nasal Spray; Nitric oxide; Prevention; SARS-CoV-2; Treatment.

All Keywords
【저자키워드】 COVID-19, Treatment, SARS-CoV-2, coronavirus, Antiviral, nitric oxide, prevention, antimicrobial, Nasal spray,