Abstract
A variety of dermatological lesions have been described in COVID-19, although the prevalence and pathogenic relationship remain unclear particularly for chilblain-like lesions. Dermatological examination was performed in a prospective cohort of consecutive patients seen at the service for SARS-CoV-2 infection. Out of 417 patients with confirmed SARS-CoV-2 infection [median age 29.5 years (range 15-65); 62.5% males], dermatological lesions were detected in 7 (1.7%). Three patients had acral lesions; their age (range) was 15-29 years; all had a negative nasopharyngeal swab and developed IgG and/or IgM-specific antibodies; all presented none or mild symptoms. A fourth patient remained negative at repeated testing; mother, father and sister had a documented mild COVID-19. Non-acral lesions were observed in four older patients, with severe COVID-19. Chilblain-like lesions may be the sole manifestation of SARS-CoV-2 infection; their presence in asymptomatic school children and adolescents should be considered a potential signal of familial or community spread of the virus.
Keywords: COVID-19; SARS-CoV-2; acral lesions; chilblain-like lesions; cutaneous lesions.
【저자키워드】 COVID-19, SARS-CoV-2, acral lesions, chilblain-like lesions, cutaneous lesions., 【초록키워드】 IgG, severe COVID-19, SARS-COV-2 infection, children, virus, Spread, Prevalence, Nasopharyngeal swab, Asymptomatic, Patient, Community, Mild, age, prospective cohort, mild symptoms, specific antibodies, mother, older patients, chilblain, school children, lesion, consecutive patients, lesions, pathogenic, service, repeated, father, sister, described, remained, was performed, variety, consecutive patient, 【제목키워드】 epidemiological, Cutaneous, manifestation, lesion, patients with SARS-CoV-2,