Abstract
Early and fast detection of COVID-19 patients help limit the transmission and wide spread of the virus in the community and will have impact on mortality by reducing the incidence of infection among vulnerable people. Therefore, community-based screening is critical. We aimed to identify clinical signs and symptoms and epidemiological features that could help discriminate confirmed cases of COVID-19 from SARS-CoV-2 negative patients. We found that age (aOR:1.02, 95%CI:1.02-1.03, p < 0.001), symptoms onset between 3 and 14 days (aOR:1.35, 95%CI:1.09)1.68, p = 0.006), fever or history of fever (aOR:1.75, 95%CI:1.42-2.14, p < 0.001), cough (aOR:1.68, 95%CI:1.31-2.04), sore throat (aOR:0.65, 95%CI:0.49-0.85, p = 0.002), ageusia (aOR:2.24, 95%CI:1.42-3.54, p = 0.001), anosmia (aOR:6.04, 95%CI:4.19-8.69, p < 0.001), chest pain (aOR:0.63, 95%CI:0.47-0.85, p = 0.003), myalgia and/or arthralgia (aOR:1.64, 95%CI:1.31-2.04, p < 0.001), household cluster (aOR:1.49, 95%CI:1.17-1.91, p = 0.001) and evidence of confirmed cases in the neighbourhood (aOR:1.92, 95%CI:1.56-2.37, p < 0.001) could help discriminate COVID-19 patients from SARS-CoV-2 negative. A screening score derived from multivariate logistic regression was developed to assess the probability of COVID-19 in patients. We suggest that a patient with a score ≥14 should undergo SARS-CoV-2 PCR testing. A patient with a score ≥30 should be considered at high risk of COVID-19 and should undergo testing but also needs prompt isolation and contact tracing.
Keywords: COVID-19; Clinical findings; Prediction; SARS-CoV-2; Score; Screening.
【저자키워드】 COVID-19, SARS-CoV-2, prediction, Clinical findings, score, Screening., 【초록키워드】 Mortality, Infection, Contact tracing, Transmission, Symptom, cough, virus, Screening, Anosmia, Spread, Probability, Clinical findings, Ageusia, clinical, Signs and symptoms, Fever, Patient, Isolation, Community, Cluster, age, Clinical signs, epidemiological, incidence, Critical, patients, COVID-19 patients, Evidence, COVID-19 patient, chest pain, myalgia, high risk, SARS-CoV-2 PCR testing, evidence of, negative patients, sore throat, confirmed case, confirmed cases, multivariate logistic regression, help, symptoms onset, arthralgia, Clinical sign, neighbourhood, feature, limit, identify, undergo, reducing, COVID-19 in patients, 【제목키워드】 clinical, Patient, epidemiological, COVID-19 patient, feature,