Abstract
Background: To detect an early increase in the inflammatory response might prove to be vital for mitigating the deleterious effects of the disease over time.
Cases: A 52-year-old obese man with moderate asthma and hypertension, who developed COVID-19 and had moderate symptoms, used a wearable device to record heart rate variability (HRV) during his illness. He had low parasympathetic tone, which decreased daily until it reached almost 2 standard deviations (SD) below normal values at the end of the second week. His sympathetic tone increased from > 3 SD to > 5 SD.
Conclusions: Conclusions: These findings suggest an altered modulation of the sympathetic and parasympathetic nervous systems in COVID-19, such that the sympathetic tone is augmented and the parasympathetic tone is reduced. Population norms of COVID-19 infections should be further studied over the short-term and using 24 h HRV measurements.
Keywords: Ambulatory monitoring; Autonomic nervous system; COVID-19; Computer-assisted signal processing; Heart rate; Wearable electronic devices..
【저자키워드】 COVID-19, heart rate, Autonomic nervous system, Ambulatory monitoring, Computer-assisted signal processing, Wearable electronic devices.., 【초록키워드】 Asthma, hypertension, Symptoms, Population, COVID-19 infection, heart, nervous system, heart rate, ambulatory, moderate, Inflammatory response, Autonomic nervous system, Standard deviation, modulation, COVID-19 infections, Variability, obese, deleterious effects, HRV, parasympathetic, detect, the disease, reduced, increase in, reached, deleterious effect, 【제목키워드】 Case report, Follow-up, heart rate, Variability,