Abstract
Kawasaki-like hyperinflammatory syndrome has been widely described as a manifestation of SARS-CoV-2 infection in paediatric patients. We report a compatible presentation and suggest that physicians consider the potential for this multisystem inflammatory syndrome to occur in adults. A 23-year-old man presented to hospital with a 4-day history of vomiting, diarrhoea, dry cough, fever and a blanching erythematous rash on hands, feet and buttocks. He was otherwise fit and healthy. On day 3 of admission, marked bilateral conjunctivitis developed and high sensitivity troponin I increased significantly, followed by acute respiratory compromise requiring high-flow nasal oxygen therapy. Transthoracic echocardiogram on day 5 showed severe global hypokinesis of the left ventricle with an ejection fraction of 22%. SARS-CoV-2 was not detected by reverse transcription PCR on nasopharyngeal swabs, sputum or stool samples, however, SARS-CoV-2 antibody was positive. The patient’s syndrome resolved and cardiomyopathy reversed completely with supportive measures. He has since made a good recovery.
Keywords: COVID-19; cardiovascular medicine; infectious diseases.
【저자키워드】 COVID-19, infectious diseases., cardiovascular medicine, 【초록키워드】 SARS-CoV-2, therapy, Infectious diseases, Diseases, SARS-COV-2 infection, hospital, High-flow nasal oxygen, oxygen, sputum, sensitivity, Adults, Stool, SARS-CoV-2 antibody, Measures, Hyperinflammatory syndrome, nasopharyngeal swabs, Fever, Patient, Oxygen therapy, Cardiomyopathy, troponin I, reverse transcription PCR, Admission, conjunctivitis, Rash, Inflammatory, stool samples, manifestation, followed by, diarrhoea, erythematous rash, Echocardiogram, Ejection fraction, left ventricle, hands, dry cough, syndrome, respiratory compromise, vomiting, physician, positive, paediatric patients, buttocks, described, significantly, healthy, occur, resolved, reversed, erythematous, 【제목키워드】 Inflammatory, syndrome,