Abstract
Objective To consider effective measures against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in medical institutions, this study estimated the SARS-CoV-2 infection rate among healthcare workers (HCWs) in Tokyo, Japan, and determined the specific findings for mild coronavirus disease 2019 (COVID-19) cases. Methods This study analyzed the results of serologic tests to detect immunoglobulin G antibodies against SARS-CoV-2 and evaluated the demographic and clinical characteristics of the faculty and HCWs at a Tokyo medical institution in August 2020. The demographic and clinical characteristics of participants with antibody-positive results were compared to those of participants with antibody-negative results. Materials This study recruited 2,341 faculty and HCWs at a Tokyo medical institution, 21 of whom had a COVID-19 history. Results Of the 2,320 participants without a COVID-19 history, 20 (0.862%) had positive serologic test results. A fever and dysgeusia or dysosmia occurred with greater frequency among the participants with positive test results than in those with negative results [odds ratio (OR), 5.475; 95% confidence interval (CI), 1.960-15.293 and OR, 24.158; 95% CI, 2.693-216.720, respectively]. No significant difference was observed in the positivity rate between HCWs providing medical care for COVID-19 patients using adequate protection and other HCWs (OR, 2.514; 95% CI, 0.959-6.588). Conclusion To reduce the risk of COVID-19 spread in medical institutions, faculty and HCWs should follow standard and necessary transmission-based precautions, and those with a fever and dysgeusia or dysosmia should excuse themselves from work as soon as possible.
Keywords: COVID-19; SARS-CoV-2; healthcare worker.
【저자키워드】 COVID-19, SARS-CoV-2, healthcare worker, 【초록키워드】 coronavirus disease, Coronavirus disease 2019, coronavirus, Healthcare workers, Clinical characteristics, antibody, SARS-COV-2 infection, Infection, severe acute respiratory syndrome Coronavirus, healthcare worker, Spread, Immunoglobulin G, dysgeusia, Immunoglobulin, HCWs, Fever, Japan, Mild, Medical care, infection rate, Care, Frequency, faculty, COVID-19 patient, Tokyo, serologic tests, HCW, serologic test, acute respiratory syndrome, significant difference, 95% CI, acute respiratory syndrome coronavirus, antibody-positive result, no significant difference, acute respiratory syndrome coronavirus 2, 95% confidence interval, measure, participant, demographic and clinical characteristics, material, positive test result, positive, precautions, objective, risk of COVID-19, dysosmia, effective, Result, greater, analyzed, detect, occurred, recruited, evaluated, reduce, the SARS-CoV-2, 【제목키워드】 institution, worker,