Abstract
The SARS-CoV-2 pandemic has strained manufacturing capacity worldwide, resulting in significant shortages of laboratory supplies both directly and indirectly. Such shortages include probe-based kits for detection of the Mycobacterium tuberculosis complex from positive liquid broth cultures. These shortages and possible loss of this particular assay have consequences for laboratory testing algorithms and public health in the United States. As there are no FDA-approved, commercially available options that currently exist which could immediately fill this gap, laboratories must identify alternatives and plan for modifying current testing algorithms to accommodate this change.
Keywords: diagnostics; gene probes; mycobacteria.
【저자키워드】 diagnostics, gene probes, mycobacteria., 【초록키워드】 public health, Tuberculosis, SARS-CoV-2 pandemic, Laboratory, Laboratory testing, Algorithm, United States, Mycobacterium tuberculosis, mycobacteria, complex, cultures, plan, alternatives, positive, The United States, consequence, resulting, identify, include, strained, 【제목키워드】 SARS-CoV-2, solution, supply, issue, current, Immediate,